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DDX3X Protein (Myc-DYKDDDDK Tag)

DDX3X 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2719282
发货至: 中国
  • 抗原 See all DDX3X 蛋白
    DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 1
    资源
    • 2
    • 2
    HEK-293 Cells
    标记
    This DDX3X protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human DDX3X protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product DDX3X 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Lin, Sivakumaran, Jones, Li, Harper, Wei, Jin, Rustanti, Meunier, Spann, Harrich: "A HIV-1 Tat mutant protein disrupts HIV-1 Rev function by targeting the DEAD-box RNA helicase DDX1." in: Retrovirology, Vol. 11, pp. 121, (2015) (PubMed).

  • 抗原
    DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))
    别名
    Ddx3x (DDX3X 产品)
    别名
    DBX Protein, DDX14 Protein, DDX3 Protein, HLP2 Protein, D1Pas1-rs2 Protein, Ddx3 Protein, Fin14 Protein, An3 Protein, pl10 Protein, DDX3X Protein, DEAD-box helicase 3, X-linked Protein, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked Protein, DEAD-box helicase 3, X-linked L homeolog Protein, DDX3X Protein, Ddx3x Protein, ddx3x.L Protein, ddx3x Protein
    背景
    The protein encoded by this gene is a member of the large DEAD-box protein family, that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif, and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity, and unlike most DEAD-box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarity to both this gene and the DDX3Y paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants.
    分子量
    73.1 kDa
    NCBI登录号
    NP_001347
    途径
    Ribonucleoprotein Complex Subunit Organization, Positive Regulation of Endopeptidase Activity, Negative Regulation of intrinsic apoptotic Signaling, Ribosome Assembly
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