CDKN1B 蛋白
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北京 101111
Quick Overview for CDKN1B 蛋白 (ABIN7938740)
抗原
See all CDKN1B 蛋白蛋白类型
宿主
资源
应用范围
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原理
- Recombinant CDKN1B protein
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Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) (AA 1-198) protein (GST tag)
CDKN1B 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) (AA 90-197) protein (His-IF2DI Tag)CDKN1B 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) (AA 1-198) protein (His-IF2DI Tag)CDKN1B 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) protein (DYKDDDDK Tag)CDKN1B 宿主: 人 宿主: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) protein (Myc-DYKDDDDK Tag)CDKN1B 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant CDKN1B protein is supplied in 25 mM Tris pH 8.0, 300 mM NaCl, 10 % glycerol, 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- CDKN1B (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))
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别名
- CDKN1B
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背景
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Protein Background: CDKN1B is a cyclin-dependent kinase inhibitor,also called cyclin-dependent kinase inhibitor p27 or p27Kip1,Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA.Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.
Short Description: Recombinant CDKN1B protein was expressed in E.coli as the full length protein (accession number NP_004055.1) with an N-terminal 6xHis tag. The molecular weight of the protein is 24.01 kDa
Aliases: cyclin-dependent kinase inhibitor p27 or p27Kip1, Important regulator of cell cycle progression
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途径
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Sensory Perception of Sound, Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Autophagy
抗原
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