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CDK1 蛋白

This Recombinant CDK1 protein is expressed in Baculovirus infected Insect Cells.
产品编号 ABIN7938734
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CDK1 蛋白 (ABIN7938734)

抗原

See all CDK1 蛋白
CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

蛋白类型

Recombinant

宿主

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资源

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Baculovirus infected Insect Cells

应用范围

Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)
  • 原理

    Recombinant CDK1 protein
  • 想要此Protein的其他选项吗?

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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 106,314.67 ¥
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    价格从 152,621.24 ¥

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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Recombinant CDK1 protein is supplied in 25 mM HEPES pH 7.5, 300 mM NaCl, 20 % glycerol, 0.04 % Triton X-100, 0.5 mM TCEP.

    注意事项

    Avoid repeated freeze/thaw cycles,keep on ice when not in storage

    储存条件

    -80 °C

    储存方法

    Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
  • 抗原

    CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

    别名

    CDK1

    背景

    Protein Background: CDK1 (Cyclin-dependent kinase 1) , also known as CDC2, CDC28A and P34CDC2. CDK1 plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset, promotes G2-M transition via association with multiple interphase cyclins. Associated with its cognate partner cyclin B, is a key enzyme for entry in mitosis and is essential for spindle morphogenesis. CDK1 up-regulates microtubule dynamics when added in cell free Xenopus extracts. CDK1inactivation is necessary for proper anaphase spindle dynamics and for cytokinesis. Large amounts of CDK1 induce the depolymerization of interphase microtubules when injected into mammalian cells and the destabilization of microtubule arrays when added on lysed mammalian cells.

    Short Description: Recombinant CDK1 protein was expressed in a baculovirus expression system as the full-length protein (accession number NP_001777.1) with an C-terminal FLAG tag. The molecular weight of CDK1 is 35.79 kDa.

    Aliases: CDC2, CDC28A, P34CDC2, Cell Division Protein Kinase 1, CDKN1, P34 Protein Kinase Cyclin-Dependent Kinase 1

    途径

    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA
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