MERTK Protein (AA 528-999)
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北京 101111
Quick Overview for MERTK Protein (AA 528-999) (ABIN7938666)
抗原
See all MERTK 蛋白蛋白类型
宿主
资源
应用范围
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产品特性
- AA 528-999
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原理
- Recombinant MER (528-999) protein
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C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) (AA 21-505) (Active) protein (mFc Tag)
MERTK 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) (AA 19-497) (Active) protein (His tag)MERTK 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) (AA 21-120) protein (GST tag)MERTK 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) protein (GST tag,His tag)MERTK 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 92 % as determined by reducing SDS-PAGE.
C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) (Active) protein (GST tag,His tag)MERTK 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 96 % as determined by SDS-PAGE Active
C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) protein (Fc Tag)MERTK 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) (AA 21-505) protein (Fc Tag)MERTK 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, AM, ADA, IA
C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) (AA 21-505) protein (His tag)MERTK 宿主: 人 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) (AA 21-505) protein (His tag)MERTK 宿主: 人 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Recombinant MER (528-999) protein is supplied in 25 mM HEPES-NaOH pH 7.5, 300 mM NaCl, 10 % glycerol, 0.04 % Triton X-100, and 0.5 mM TCEP.
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注意事项
- Avoid repeated freeze/thaw cycles,keep on ice when not in storage
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储存条件
- -80 °C
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储存方法
- Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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- MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))
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别名
- MER
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背景
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Protein Background: MERTK (MER Proto-Oncogene, Tyrosine Kinase) is a receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including LGALS3, TUB, TULP1 or GAS6. MER regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells (efferocytosis). Ligand binding at the cell surface induces autophosphorylation of MERTK on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, MERTK interacts with GRB2 or PLCG2 and induces phosphorylation of MAPK1, MAPK2, FAK/PTK2 or RAC1. Diseases associated with MERTK include Retinitis Pigmentosa 38 and Retinitis Pigmentosa.
Short Description: Recombinant MER(528-999) protein that includes amino acids 528-999 of human MER protein (accession number NP_006334.2) was expressed in a baculovirus expression system, and contains an N-terminal FLAG tag. The molecular weight of the protein is 54 kDa.
Aliases: MER Proto-Oncogene Tyrosine Kinase, MERTK
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途径
- RTK signaling
抗原
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