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ALKBH1 蛋白

This Recombinant ALKBH1 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7938583
发货至: 中国
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Quick Overview for ALKBH1 蛋白 (ABIN7938583)

抗原

See all ALKBH1 蛋白
ALKBH1 (AlkB, Alkylation Repair Homolog 1 (ALKBH1))

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

应用范围

Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)
  • 原理

    Recombinant ALKBH1 protein

    产品特性

    ALKBH1 (AlkB Homolog 2, Alpha-Ketoglutarate Dependent Dioxygenase) is a member of ALKBH protein family. It can repair alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. ALKBH1 can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. It can release modified bases from both DNA and RNA. The oxidative demethylation requires molecular oxygen, alpha-ketoglutarate and iron.
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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 116,946.14 ¥
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    Conjugate Strep Tag
    Origin Human
    价格从 145,985.55 ¥

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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Recombinant ALKBH1 protein is supplied in 25 mM Tris-HCl pH 8.0, 300 mM NaCl, 10 % glycerol, and 0.5 mM TCEP.

    注意事项

    Avoid repeated freeze/thaw cycles,keep on ice when not in storage

    储存条件

    -80 °C

    储存方法

    Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
  • 抗原

    ALKBH1 (AlkB, Alkylation Repair Homolog 1 (ALKBH1))

    别名

    ALKBH1

    背景

    Protein Background: ALKBH1 (AlkB Homolog 2, Alpha-Ketoglutarate Dependent Dioxygenase) is a member of ALKBH protein family. It can repair alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. ALKBH1 can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. It can release modified bases from both DNA and RNA. The oxidative demethylation requires molecular oxygen, alpha-ketoglutarate and iron.

    Short Description: Full length ALKBH1 protein (accession number NP_006011.2) was expressed in E.coli cells with an N-terminal 6xHis Tag. The molecular weight of ALKBH1 is 47.6 kDa.

    Aliases: AlkB Homolog 1, Histone H2A Dioxygenase

    途径

    DNA Damage Repair
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