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14-3-3 zeta Protein (YWHAZ)

This Recombinant 14-3-3 zeta protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7938564
发货至: 中国
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Quick Overview for 14-3-3 zeta Protein (YWHAZ) (ABIN7938564)

抗原

See all 14-3-3 zeta (YWHAZ) 蛋白
14-3-3 zeta (YWHAZ)

蛋白类型

Recombinant

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大肠杆菌(E. Coli)

应用范围

Activity Assay (AcA), Functional Studies (Func), Screening Assay (ScA)
  • 原理

    Recombinant YWHAZ protein
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    表达系统
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Recombinant YWHAZ protein is supplied in 25 mM Tris pH 8.0, 300 mM NaCl, 20 % glycerol, 0.5 mM TCEP.

    注意事项

    Avoid repeated freeze/thaw cycles,keep on ice when not in storage

    储存条件

    -80 °C

    储存方法

    Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
  • 抗原

    14-3-3 zeta (YWHAZ)

    别名

    YWHAZ

    背景

    Protein Background: YWHAZ (14-3-3 protein zeta/delta) is a adapter protein, Implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Promotes cytosolic retention and inactivation of TFEB transcription factor by binding to phosphorylated TFEB. Induces ARHGEF7 activity on RAC1 as well as lamellipodia and membrane ruffle formation.

    Short Description: Recombinant YWHAZ protein that includes full length of human YWHAZ protein (accession number NP_001129171.1) was expressed in E. coli and contains an N-terminal His tag with a molecular weight of 29.91 kDa. The purity of the protein is ≥ 95 % by SDS-PAGE.

    Aliases: 14-3-3 Protein Zeta/Delta, KCIP, Activation Protein, Delta Polypeptide, YWHAD, HEL4, Protein Kinase C, Inhibitor Protein 1

    途径

    Apoptosis, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
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