FGF23 蛋白
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北京 101111
Quick Overview for FGF23 蛋白 (ABIN7937380)
抗原
See all FGF23 蛋白蛋白类型
生物活性
宿主
资源
纯度
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原理
- Recombinant Human Fibroblast Growth Factor 23
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序列
- YPNASPLLGS SWGGLIHLYT ATARNSYHLQ IHKNGHVDGA PHQTIYSALM IRSEDAGFVV ITGVMSRRYL CMDFRGNIFG SHYFDPENCR FQHQTLENGY DVYHSPQYHF LVSLGRAKRA FLPGMNPPPY SQFLSRRNEI PLIHFNTPIP RRHTRSAEDD SERDPLNVLK PRARMTPAPA SCSQELPSAE DNSPMASDPL GVVRGGRVNT HAGGTGPEGC RPFAKFI
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过滤
- 0.2 μm filtered
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内毒素水平
- Less than 1 EU/ug of rHuFGF-23 as determined by LAL method.
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Biological Activity Comment
- Fully biologically active when compared to standard. The ED50 as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 0.5 μg/ml, corresponding to a specific activity of > 2.0 x103 IU/mg in the presence of 0.3 μg/ml of rMuKlotho and 10 μg/ml of heparin.
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说明
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Approximately 25.3 kDa, a single non-glycosylated polypeptide chain containing 227 amino acids.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
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有效期
- 12 months
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- FGF23 (Fibroblast Growth Factor 23 (FGF23))
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别名
- Fibroblast Growth Factor 23
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分子量
- 25.3 kDa
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基因ID
- 8074
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UniProt
- Q9GZV9
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion
抗原
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