FLT3LG 蛋白
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北京 101111
Quick Overview for FLT3LG 蛋白 (ABIN7866465)
抗原
See all FLT3LG 蛋白蛋白类型
生物活性
宿主
资源
纯度
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原理
- Recombinant Human Flt-3 Ligand Protein
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序列
- TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTA
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特异性
- Chromosomal location:19q13.3
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产品特性
- Length (aa):155
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内毒素水平
- < 0.1 ng/μg of protein (< 1EU/μg)
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应用备注
- Determined by the dose-dependent stimulation of the proliferation of human AML5 cells. The expected ED50 for this effect is 0,5 - 1 ng/mL.
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限制
- 仅限研究用
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- FLT3LG (Fms-Related tyrosine Kinase 3 Ligand (FLT3LG))
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别名
- Flt-3 Ligand
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背景
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Synonyms: FLT3, FLK2, STK1, CD135, FLK-2
Description: Flt3-ligand (flk2-ligand) stimulates the proliferation and colony formation of certain BM precursor cells including CD34+ cells. Flt3-ligand produced in E. coli is a soluble non-glycosylated 17.6 kDa polypeptide containing 155 amino acid residues which comprises the extracellular domain of the transmembrane flt3-ligand protein.
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分子量
- 17.6 kDa
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基因ID
- 2323
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NCBI登录号
- NM_001459, NP_001450
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UniProt
- P49771
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途径
- RTK signaling
抗原
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