TLR3 Protein (AA 24-904)
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北京 101111
Quick Overview for TLR3 Protein (AA 24-904) (ABIN7866071)
抗原
See all TLR3 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 24-904
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原理
- Human TLR3 Protein Recombinant
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序列
- STTKCTVSHE VADCSHLKLT QVPDDLPTNI TVLNLTHNQL RRLPAANFTR YSQLTSLDVG FNTISKLEPE LCQKLPMLKV LNLQHNELSQ LSDKTFAFCT NLTELHLMSN SIQKIKNNPF VKQKNLITLD LSHNGLSSTK LGTQVQLENL QELLLSNNKI QALKSEELDI FANSSLKKLE LSSNQIKEFS PGCFHAIGRL FGLFLNNVQL GPSLTEKLCL ELANTSIRNL SLSNSQLSTT SNTTFLGLKW TNLTMLDLSY NNLNVVGNDS FAWLPQLEYF FLEYNNIQHL FSHSLHGLFN VRYLNLKRSF TKQSISLASL PKIDDFSFQW LKCLEHLNME DNDIPGIKSN MFTGLINLKY LSLSNSFTSL RTLTNETFVS LAHSPLHILN LTKNKISKIE SDAFSWLGHL EVLDLGLNEI GQELTGQEWR GLENIFEIYL SYNKYLQLTR NSFALVPSLQ RLMLRRVALK NVDSSPSPFQ PLRNLTILDL SNNNIANIND DMLEGLEKLE ILDLQHNNLA RLWKHANPGG PIYFLKGLSH LHILNLESNG FDEIPVEVFK DLFELKIIDL GLNNLNTLPA SVFNNQVSLK SLNLQKNLIT SVEKKVFGPA FRNLTELDMR FNPFDCTCES IAWFVNWINE THTNIPELSS HYLCNTPPHY HGFPVRLFDT SSCKDSAPFE L
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产品特性
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Protein Size: Recombinant TLR3 migrates as an approximately 75 kDa protein due to glycosylation under reducing conditions in SDS-PAGE.
Sequence Position: Optimized DNA sequence encoding Human TLR3 mature chain was expressed in CHO. Recombinant Human Toll-like receptor 3 encodes amino acid residues 24-904.
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内毒素水平
- Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/μg(1EU/μg).
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Biological Activity Comment
- Determined by its ability to neutralize Poly I:C induced NF-κB signaling in HT-29 cells stably transfected with NF-κB-luc. The ED50 for this effect is 5-10 μg/ml.
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Toll-Like Receptor 3 (TLR3) (AA 23-703) (Active) protein (His tag)
TLR3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Toll-Like Receptor 3 (TLR3) (AA 26-705) (Active) protein (His tag)TLR3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Toll-Like Receptor 3 (TLR3) (AA 31-711) (Active) protein (His tag)TLR3 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Toll-Like Receptor 3 (TLR3) (AA 601-700) protein (GST tag)TLR3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Toll-Like Receptor 3 (TLR3) (AA 23-703) protein (His tag,Biotin)TLR3 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Toll-Like Receptor 3 (TLR3) protein (His tag)TLR3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE
Toll-Like Receptor 3 (TLR3) (AA 24-704) protein (Fc Tag)TLR3 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Toll-Like Receptor 3 (TLR3) (AA 24-704) protein (mFc Tag)TLR3 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
Toll-Like Receptor 3 (TLR3) (AA 24-704) protein (His tag)TLR3 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. AM, ADA, IA, ScA
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
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缓冲液
- TLR3 was Lyophilized from PBS, pH 7.2.
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储存条件
- 4 °C,-20 °C
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储存方法
- The lyophilized protein is stable for at least 2 years from date of receipt at -20°C. Upon reconstitution, this product can be stored in working aliquots at 2°- 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
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有效期
- 24 months
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- TLR3 (Toll-Like Receptor 3 (TLR3))
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别名
- TLR3
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分子量
- 75 kDa
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途径
- TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
抗原
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