BDNF 蛋白
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北京 101111
Quick Overview for BDNF 蛋白 (ABIN7849701)
抗原
See all BDNF 蛋白蛋白类型
宿主
资源
应用范围
纯度
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原理
- Recombinant Human /Mouse/Rat BDNF Protein
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过滤
- 0.2 μm filtered
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内毒素水平
- <0.01EU/μg by LAL test
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Dissolve the lyophilized protein in distilled water(It is not recommended to reconstitute to a concentration <100 μg/mL.)
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 400 mM NaCl, pH 7.2.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Ship at 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- BDNF (Brain-Derived Neurotrophic Factor (BDNF))
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别名
- BDNF
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背景
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Synonyms: Brain-derived neurotrophic factor, BDNF, brain-derived neurotrophic factor, ANON2, BULN2, brain derived neurotrophic factor
Description: Recombinant human BDNF is produced by the E.coli system, with the target gene encoding His129-Arg247 expressed.
Background: Brain-derived neurotrophic factor, also known as BDNF, is a prosurvival factor induced by cortical neurons that is necessary for survival of striatal neurons in the brain. BDNF is a member of the "neurotrophin" family of growth factors, which are related to the NGF. It acts on certain neurons of the central nervous system and the peripheral nervous system, helping to support the survival of existing neurons, and encourage the growth and differentiation of new neurons and synapses. In the brain, it is active in the hippocampus, cortex, and basal forebrain-areas vital to learning, memory, and higher thinking. Post mortem analysis has shown lowered levels of BDNF in the brain tissues of people with Alzheimer's disease.
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UniProt
- P23560
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途径
- RTK signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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