Abeta 1-42 蛋白
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北京 101111
Quick Overview for Abeta 1-42 蛋白 (ABIN7849653)
抗原
蛋白类型
宿主
资源
应用范围
纯度
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原理
- Recombinant Human Amyloid beta 1-42, AB1-42 Protein
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.01M PBS, pH 7.5.
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储存条件
- 4 °C,-20 °C
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储存方法
- Ship at 4°C. Upon receipt, aliquot and store at -20°C for long term. Avoid repeated freeze and thaw cycles.
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- Abeta 1-42 (Amyloid beta 1-42 (Abeta 1-42))
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别名
- AB1-42
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背景
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Synonyms: Beta Amyloid(1-42), beta Amyloid 1-42, beta-Amyloid 1-42, Amyloid 1-42, A4, ABETA, ABPP, Alzheimers Disease Amyloid Protein, Amyloid B, Amyloid Beta A4 Protein Precursor, Amyloid Beta, Amyloid of Aging and Alzheimer Disease, B Amyloid, Beta APP, Cerebral Vascular Amyloid Peptide, Beta-amyloid protein 42
Description: Recombinant mature human AB1-42 protein.
Background: Amyloid beta (Aβ or Abeta) denotes peptides of 36-43 amino acids that are crucially involved in Alzheimer's disease as the main component of the amyloid plaques found in the brains of Alzheimer patients. Oligomeric amyloid-β 1-42 (Aβ-42) peptides are considered to be the most toxic species connected to the occurrence of Alzheimer's disease. Unstructured oligomeric Aβ-42 interacted with membrane bilayers of giant unilamellar vesicles (GUV) and neuronal model cells, facilitated cellular uptake of Aβ-42, and inhibition of mitochondrial activity. Elevated concentrations of glucose within the range observed in diabetic individuals (10 mM) facilitate the formation of membrane-active Aβ-42 oligomers.
抗原
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