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Transferrin Protein (TF) (Holo)

This Recombinant Transferrin protein is expressed in HEK 293 Cells.
产品编号 ABIN7833114
发货至: 中国
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Quick Overview for Transferrin Protein (TF) (Holo) (ABIN7833114)

抗原

See all Transferrin (TF) 蛋白
Transferrin (TF)

蛋白类型

Recombinant

生物活性

Active

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HEK 293 Cells

应用范围

Cell Culture (CC)

纯度

More than 98% by SDS-PAGE

质量等级

Animal-Free
  • 产品特性

    Holo

    原理

    Human holo-Transferrin (Animal free) protein

    序列

    AA 679

    Biological Activity Comment

    The biological activity is determined by the stimulation of cell proliferation of MDCK cells in serum-free cell culture medium.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge the vial prior to opening. Do not vortex. The lyophilized HTF should be reconstituted in water to a concentration of 1.0 mg/mL.

    缓冲液

    PBS (pH 7.4)

    储存条件

    4 °C/-20 °C/-80 °C

    储存方法

    The lyophilized HTF is stable at room temperature for 1 month and at 2 °C to 8 °C for 6 months. Reconstituted working aliquots are stable for 1 week at 2°C to 8°C and for 3 months at -20°C to -80°C.

    有效期

    6 months
  • 抗原

    Transferrin (TF)

    别名

    Transferrin

    背景

    Description: Transferrin (TF) is found in vertebrate that mediates the transport of iron through blood plasma. When not bound to iron, the protein is known as apo-Transferrin. Each molecule contains two binding sites for iron in the ferric form Fe(III). The iron-bound holo-Transferrin (HTF) can bind to the dimeric Transferrin receptor (TfR) on a cell’s surface and is subsequently internalized by endocytosis. A reduction of pH in the vesicle decreases its iron-affinity and causes HTF to release bound iron ions. Transferrin appears to be essential for most cells growing in tissue culture. ReliaTech's Recombinant Human holo-Transferrin is a 76 kDa glycoprotein consisting of 679 amino acid residues.
    Synonyms: HTF, Serotransferrin, Transferrin, TF, Holo Transferrin, Beta-1 metal-binding-globulin, Siderophilin

    分子量

    76 kDa

    NCBI登录号

    NP_001054

    UniProt

    P02787

    途径

    Transition Metal Ion Homeostasis
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