Transferrin Protein (TF) (Holo)
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Quick Overview for Transferrin Protein (TF) (Holo) (ABIN7833114)
抗原
See all Transferrin (TF) 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
质量等级
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产品特性
- Holo
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原理
- Human holo-Transferrin (Animal free) protein
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序列
- AA 679
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Biological Activity Comment
- The biological activity is determined by the stimulation of cell proliferation of MDCK cells in serum-free cell culture medium.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge the vial prior to opening. Do not vortex. The lyophilized HTF should be reconstituted in water to a concentration of 1.0 mg/mL.
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缓冲液
- PBS (pH 7.4)
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储存条件
- 4 °C/-20 °C/-80 °C
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储存方法
- The lyophilized HTF is stable at room temperature for 1 month and at 2 °C to 8 °C for 6 months. Reconstituted working aliquots are stable for 1 week at 2°C to 8°C and for 3 months at -20°C to -80°C.
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有效期
- 6 months
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- Transferrin (TF)
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别名
- Transferrin
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背景
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Description: Transferrin (TF) is found in vertebrate that mediates the transport of iron through blood plasma. When not bound to iron, the protein is known as apo-Transferrin. Each molecule contains two binding sites for iron in the ferric form Fe(III). The iron-bound holo-Transferrin (HTF) can bind to the dimeric Transferrin receptor (TfR) on a cell’s surface and is subsequently internalized by endocytosis. A reduction of pH in the vesicle decreases its iron-affinity and causes HTF to release bound iron ions. Transferrin appears to be essential for most cells growing in tissue culture. ReliaTech's Recombinant Human holo-Transferrin is a 76 kDa glycoprotein consisting of 679 amino acid residues.
Synonyms: HTF, Serotransferrin, Transferrin, TF, Holo Transferrin, Beta-1 metal-binding-globulin, Siderophilin -
分子量
- 76 kDa
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NCBI登录号
- NP_001054
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UniProt
- P02787
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途径
- Transition Metal Ion Homeostasis
抗原
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