Cathepsin L Protein (His tag)
Quick Overview for Cathepsin L Protein (His tag) (ABIN7794657)
抗原
See all Cathepsin L (CTSL1) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This Cathepsin L protein is labelled with His tag.
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原理
- Recombinant human CTSL Protein with C-terminal 10?His tag
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Cathepsin L1 (CTSL1) (AA 18-333) protein (His-IF2DI Tag)
CTSL1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Cathepsin L1 (CTSL1) (AA 18-333) protein (GST tag)CTSL1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cathepsin L1 (CTSL1) (AA 1-333) protein (GST tag)CTSL1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cathepsin L1 (CTSL1) (AA 1-334) protein (His tag)CTSL1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Cathepsin L1 (CTSL1) (AA 18-334) protein (His tag)CTSL1 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 90 % SDS
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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- Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))
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别名
- CTSL
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背景
- MEP, CATL, CTSL1 Background: The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Additionally, this protein cleaves the S1 subunit of the SARS-CoV-2 spike protein, which is necessary for entry of the virus into the cell. [provided by RefSeq, Aug 2020]
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分子量
- Predicted: 37.2 kDa after removal of the signal peptide. The apparent molecular mass of CTSL-His is approximately 35-55 kDa due to glycosylation.
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UniProt
- P07711
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途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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