Clusterin Protein (CLU) (His tag)
Quick Overview for Clusterin Protein (CLU) (His tag) (ABIN7668544)
抗原
See all Clusterin (CLU) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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标记
- This Clusterin protein is labelled with His tag.
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原理
- Recombinant Rat Clusterin/ApoJ protein (His tag)
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序列
- Glu 22-Arg 226
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纯化方法
- > 95 % as determined by reducing SDS-PAGE.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 10 EU/mg of the protein as determined by the LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- Clusterin (CLU)
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别名
- Clusterin,ApoJ
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背景
- Clusterin is a secreted protein which belongs to the Clusterin family. Clusterin is expressed in adult testis, heart, ovary, adrenal gland, brain and liver. Clusterin has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. In addition,Clusterin is up/ down regulated on the mRNA or protein level in many pathological and clinically relevant situations including cancer, organ regeneration, infection, Alzheimer disease, retinitis pigmentosa, myocardial infarction, renal tubular damage, autoimmunity and others.,AAG4,AP,APOJ,Aging-Associated Gene 4 Protein,Apo-J,Apolipoprotein J,CLI,CLU,Clusterin,Complement Cytolysis Inhibitor,Complement-Associated Protein SP-40,KUB1,Ku70-Binding Protein 1,NA1/NA2,TRPM-2,Testosterone-Repressed Prostate Message 2
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分子量
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calculated_mw: 22.4 kDa
observed_mw: 28 kDa
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UniProt
- P05371
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途径
- Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
抗原
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