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CD96 Protein (CD96) (His tag)

This Recombinant CD96 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7668408
发货至: 中国

Quick Overview for CD96 Protein (CD96) (His tag) (ABIN7668408)

抗原

See all CD96 蛋白
CD96

蛋白类型

Recombinant

生物活性

Inactive

宿主

  • 17
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小鼠

资源

  • 10
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大肠杆菌(E. Coli)

纯度

> 95 %
  • 标记

    This CD96 protein is labelled with His tag.

    原理

    Recombinant Mouse CD96/TACTILE protein (His tag)

    序列

    Val 22-Phe 174

    过滤

    0.2 μm filtered

    内毒素水平

    < 10 EU/mg of the protein as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

    缓冲液

    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    CD96

    别名

    CD96,TACTILE

    背景

    The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. The CD155 ligand CD96 is a member of the Ig superfamily. It's a immunoglobulin-like protein tentatively allocated to the repertoire of human NK receptors. NK cells recognize poliovirus receptor (PVR), a nectins and nectin-like protein family member serve to mediate cell-cell adhesion, cell migration, with the presence of an additional receptor, CD96. CD96 promotes NK cell adhesion to target cells expressing PVR, stimulates cytotoxicity of activated NK cells, and mediates acquisition of PVR from target cells. The effect the cells with mutated CD96 protein lost adhesion and growth activities indicates that CD96 mutations may cause a form of the C syndrome by interfering with cell adhesion and growth.,Cell surface antigen CD,Cell surface antigen CD96,T cell-activated increased late expression protein,T-cell surface protein tactile,Cd96,TACTILE

    分子量

    calculated_mw: 16.7 kDa

    observed_mw: 22 kDa

    UniProt

    Q3U0X8
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