Calnexin Protein (CANX) (His tag)
This Recombinant Calnexin protein is expressed in 大肠杆菌（E. Coli）.
产品编号 ABIN7668286
发货至:
中国
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Quick Overview for Calnexin Protein (CANX) (His tag) (ABIN7668286)
抗原
See all Calnexin (CANX) 蛋白
Calnexin (CANX)
蛋白类型
Recombinant
生物活性
Inactive
宿主
人
资源
大肠杆菌（E. Coli）
纯度
> 95 %
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标记
- This Calnexin protein is labelled with His tag.
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原理
- Recombinant Human Calnexin/CANX protein (His tag)
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序列
- His 21-Leu 251
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纯化方法
- > 95 % as determined by reducing SDS-PAGE.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 10 EU/mg of the protein as determined by the LAL method.
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Calnexin (CANX) (AA 21-481) protein
CANX 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- Calnexin (CANX)
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别名
- Calnexin,CANX
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背景
- Calnexin/CANX is a single-pass type I membrane protein which belongs to the calreticulin family. It consists of a large N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic tail. The function of calnexin is to retain unfolded or unassembled N-linked glycoproteins in the endoplasmic reticulum. Calnexin is a calcium-binding protein that interacts briefly with newly synthesized glycoproteins in the endoplasmic reticulum. Calnexin may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. Calnexin seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Calnexin dwindles with aging and might contribute to a cytoprotection in an array of human age-related diseases.,CANX,Calnexin,IP90,Major Histocompatibility Complex Class I Antigen-Binding Protein p88,p90
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分子量
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calculated_mw: 25.3 kDa
observed_mw: 42 kDa
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UniProt
- P27824
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途径
- MAPK Pathway, Thyroid Hormone Synthesis
抗原
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