Calnexin Protein (CANX) (His tag)
This Recombinant Calnexin protein is expressed in 大肠杆菌（E. Coli）.
Quick Overview for Calnexin Protein (CANX) (His tag) (ABIN7668286)
抗原
See all Calnexin (CANX) 蛋白
Calnexin (CANX)
蛋白类型
Recombinant
生物活性
Inactive
宿主
人
资源
大肠杆菌（E. Coli）
纯度
> 95 %
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标记
- This Calnexin protein is labelled with His tag.
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原理
- Recombinant Human Calnexin/CANX protein (His tag)
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序列
- His 21-Leu 251
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纯化方法
- > 95 % as determined by reducing SDS-PAGE.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 10 EU/mg of the protein as determined by the LAL method.
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Calnexin (CANX) (AA 21-481) protein
CANX 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % -8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- Calnexin (CANX)
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别名
- Calnexin,CANX
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背景
- Calnexin/CANX is a single-pass type I membrane protein which belongs to the calreticulin family. It consists of a large N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic tail. The function of calnexin is to retain unfolded or unassembled N-linked glycoproteins in the endoplasmic reticulum. Calnexin is a calcium-binding protein that interacts briefly with newly synthesized glycoproteins in the endoplasmic reticulum. Calnexin may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. Calnexin seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Calnexin dwindles with aging and might contribute to a cytoprotection in an array of human age-related diseases.,CANX,Calnexin,IP90,Major Histocompatibility Complex Class I Antigen-Binding Protein p88,p90
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分子量
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calculated_mw: 25.3 kDa
observed_mw: 42 kDa
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UniProt
- P27824
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途径
- MAPK Pathway, Thyroid Hormone Synthesis
抗原
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