ADGRE5 (AA 21-530) protein (His tag)
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Quick Overview for ADGRE5 (AA 21-530) protein (His tag) (ABIN7668120)
抗原
蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 21-530
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标记
- His tag
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原理
- Recombinant Human ADGRE5 Protein(His Tag)
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序列
- Gln21-Leu530
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纯化方法
- SDS-PAGE analysis of Human ADGRE5 proteins, 2 μg/lane of Recombinant Human ADGRE5 proteins was resolved with an SDS-PAGE under reducing conditions, showing bands at 55.9KD
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU/mg of the protein as determined by the LAL method
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Biological Activity Comment
- Not validated for activity
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution in PBS with 5 % Trehalose and 5 % Mannitol.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- ADGRE5
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背景
- ADGRE5,Adhesion G protein-coupled receptor E5,CD 97,CD_antigen=CD97,CD97,CD97 antigen,CD97 antigen subunit beta,CD97 Molecule,CD97,Leukocyte antigen CD97,Seven span transmembrane protein,Seven transmembrane helix receptor,Seven transmembrane heterodimeric receptor associated with inflammation,TM7LN 1,TM7LN1,This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with an 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with an other EGF-TM7 genes on the short arm of chromosome 19.
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分子量
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Calculated MW: 55.9 kDa
Observed MW: 80-100 kDa
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基因ID
- 976
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UniProt
- P48960
抗原
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