CCR7 蛋白
Quick Overview for CCR7 蛋白 (ABIN7597218)
抗原
See all CCR7 蛋白蛋白类型
宿主
资源
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原理
- Human CCR7 full length protein-MNP
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Chemokine (C-C Motif) Receptor 7 (CCR7) protein
CCR7 宿主: 人 宿主: HEK-293 Cells Synthetic Nanodisc
Chemokine (C-C Motif) Receptor 7 (CCR7) (AA 25-59) protein (Fc Tag)CCR7 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-C Motif) Receptor 7 (CCR7) protein (Myc-DYKDDDDK Tag)CCR7 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from PBS. Normally 5% – 8% trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
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别名
- CCR7
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背景
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BLR2, CC-CKR-7, CCR-7, CD197, CDw197, CMKBR7, EBI1
The protein is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. -
分子量
- The human full length CCR7 protein has a MW of 42.9 kDa
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UniProt
- P32248
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途径
- Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
抗原
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