GRIN2C Protein (DYKDDDDK Tag,Strep Tag)
GRIN2C
宿主: 人
宿主: HEK-293 Cells
Synthetic Nanodisc
Imm, ELISA, cryo-EM, PhD, SPR
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- 抗原 See all GRIN2C 蛋白
- GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))
- 蛋白类型
- Synthetic Nanodisc
- 宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This GRIN2C protein is labelled with DYKDDDDK Tag,Strep Tag.
- 应用范围
- Immunogen (Imm), ELISA, Cryogenic electron microscopy (cryo-EM), Phage Display (PhD), Surface Plasmon Resonance (SPR)
- 原理
- Human NMDE3-Strep full length protein-synthetic nanodisc
- Top Product
- Discover our top product GRIN2C 蛋白
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Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C) (AA 1-171) protein (GST tag)
GRIN2C 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 说明
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Advantages:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Mammalian cell expression system ensures post- translational modifications
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- GRIN2C (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2c (GRIN2C))
- 别名
- NMDE3 (GRIN2C 产品)
- 背景
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GluN2C, NMDAR2C, NR2C
This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptor, which is a subtype of ionotropic glutamate receptor. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013] - 分子量
- The human full length NMDE3-Strep protein has a MW of 134.2 kDa
- UniProt
- Q14957
- 途径
- Synaptic Membrane
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