SCNN1A Protein (DYKDDDDK Tag,Strep Tag)
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- 抗原 See all SCNN1A 蛋白
- SCNN1A (Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This SCNN1A protein is labelled with DYKDDDDK Tag,Strep Tag.
- 应用范围
- Immunogen (Imm), ELISA, Cryogenic electron microscopy (cryo-EM), Phage Display (PhD), Surface Plasmon Resonance (SPR)
- 原理
- Human SCNNA-Strep full length protein-synthetic nanodisc
- Top Product
- Discover our top product SCNN1A 蛋白
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- 说明
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Advantages:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Mammalian cell expression system ensures post- translational modifications
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- SCNN1A (Sodium Channel, Nonvoltage-Gated 1 alpha (SCNN1A))
- 别名
- SCNNA (SCNN1A 产品)
- 背景
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BESC2, ENaCa, ENaCalpha, LIDLS3, SCNEA, SCNN1
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2009] - 分子量
- The human full length SCNNA-Strep protein has a MW of 75.7 kDa
- UniProt
- P37088
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