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IL-2 Protein (C160S)

This Recombinant IL-2 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7596214
发货至: 中国

Quick Overview for IL-2 Protein (C160S) (ABIN7596214)

抗原

See all IL-2 (IL2) 蛋白
IL-2 (IL2) (Interleukin 2 (IL2))

蛋白类型

Recombinant

生物活性

Active

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小鼠

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大肠杆菌(E. Coli)

应用范围

SDS-PAGE (SDS), Activity Assay (AcA)

纯度

> 90% by SDS-PAGE
  • 产品特性

    C160S

    序列

    MAPTSSSTSS STAEAQQQQQ QQQQQQQHLE QLLMDLQELL SRMENYRNLK LPRMLTFKFY LPKQATELKD LQCLEDELGP LRHVLDLTQS KSFQLEDAEN FISNIRVTVV KLKGSDNTFE CQFDDESATV VDFLRRWIAF SQSIISTSPQ

    内毒素水平

    < 1 EU per 1ug of protein (determined by LAL method)

    Biological Activity Comment

    Measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells. The ED50 range ≤0.9ng/ml.
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • 抗原

    IL-2 (IL2) (Interleukin 2 (IL2))

    别名

    IL-2

    背景

    IL2 (Interleukin2), also known as T cell growth factor (TCGF), is an immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant mouse IL2 was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

    分子量

    17.3 kDa (150aa) confirmed by MALDI-TOF

    NCBI登录号

    NP_032392

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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