ABCB11 Protein (AA 1-1321) (His tag)
custom-made
ABCB11
宿主: 小鼠
宿主: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
-
- 抗原 See all ABCB11 蛋白
- ABCB11 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-1321
-
宿主
- 小鼠
-
资源
- HEK-293 Cells
- 标记
- This ABCB11 protein is labelled with His tag.
- 原理
- Made-to-order recombinant Abcb11 Protein expressed in mammalian cells.
- 序列
- MSDSVILRSV KKFGEENHAF ESDGFHNNDK KSRLQDKKKG EGARVGFFEL FRFSSSKDNW LMFMGSVCAL LHGMAQPGMI IVFGILTDIF VEYDIERQEL SIPEKVCMNN TIVWINSSFN QNMTNGTSCG LVDINSEVIK FSGIYAGVGV AVLILGYFQI RLWVITGARQ IRKMRKFYFR RIMRMEIGWF DCTSVGELNS RFSDDINKID EAIADQMALF LQRLSTALSG LLLGFYRGWK LTLVILAVSP LIGIGAAVIG LSVAKFTELE LKAYAKAGSI ADEVLSSIRT VAAFGGENKE VERYEKNLMF AQRWGIWKGM VMGFFTGYMW CLIFFCYALA FWYGSRLVLD EGEYTPGTLI QIFLCVIIAA MNIGNASSCL EIFSTGCSAA SSIFQTIDRQ PVMDCMSGDG YKLDRIKGEI EFHNVTFHYP SRPEVKILNN LSMVIKPGET TAFVGSSGAG KSTALQLIQR FYDPCEGMVT LDGHDIRSLN IRWLRDQIGI VEQEPVLFST TIAENIRLGR EEATMEDIVQ AAKDANAYNF IMALPQQFDT LVGEGGGQMS GGQKQRVAIA RALIRKPKIL LLDMATSALD NESEAKVQGA LNKIQHGHTI ISVAHRLSTV RSADVIIGFE HGTAVERGTH EELLERKGVY FMLVTLQSQE DNTHKETGIK GKDTTEGDTP ERTFSRGSYQ DSLRASIRQR SKSQLSHLSH EPPLAIGDHK SSYEDRKDND VLVEEVEPAP VRRILKYNIS EWPYILVGAL CAAINGAVTP IYSLLFSQIL KTFSLVDKEQ QRSEIYSMCL FFVILGCVSL FTQFLQGYNF AKSGELLTKR LRKFGFKAML RQDIGWFDDL KNNPGVLTTR LATDASQVQG ATGSQVGMMV NSFTNIFVAV LIAFLFNWKL SLVISVFFPF LALSGAVQTK MLTGFASQDK EILEKAGQIT NEALSNIRTV AGIGVEGRFI KAFEVELEKS YKTAIRKANV YGLCYAFSQG ISFLANSAAY RYGGYLIVYE DLNFSYVFRV VSSIAMSATA VGRTFSYTPS YAKAKISAAR FFQLLDRKPP IDVYSGAGEK WDNFQGKIDF IDCKFTYPSR PDIQVLNGLS VSVDPGQTLA FVGSSGCGKS TSIQLLERFY DPDQGTVMID GHDSKKVNVQ FLRSNIGIVS QEPVLFDCSI MDNIKYGDNT KEISVERAIA AAKQAQLHDF VMSLPEKYET NVGIQGSQLS RGEKQRIAIA RAIVRDPKIL LLDEATSALD TESEKTVQLA LDKAREGRTC IVIAHRLSTI QNSDIIAVMS QGVVIEKGTH KKLMDQKGAY YKLVITGAPI S Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- 特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- 产品特性
-
Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- 质量等级
- custom-made
- Top Product
- Discover our top product ABCB11 蛋白
-
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) (AA 1-1321) protein (His tag)
custom-made ABCB11 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
-
- 应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- The buffer composition is at the discretion of the manufacturer.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C.
- 有效期
- 12 months
-
- 抗原
- ABCB11 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11))
- 别名
- Abcb11 (ABCB11 产品)
- 背景
- Bile salt export pump (EC 7.6.2.-) (ATP-binding cassette sub-family B member 11) (Sister of P-glycoprotein),FUNCTION: Catalyzes the transport of the major hydrophobic bile salts, such as taurine and glycine-conjugated cholic acid across the canalicular membrane of hepatocytes in an ATP-dependent manner, therefore participates in hepatic bile acid homeostasis and consequently to lipid homeostasis through regulation of biliary lipid secretion in a bile salts dependent manner (PubMed:14570929, PubMed:11172067, PubMed:23764895, PubMed:22619174, PubMed:19228692). Transports taurine-conjugated bile salts more rapidly than glycine-conjugated bile salts (By similarity). Also transports non-bile acid compounds, such as pravastatin and fexofenadine in an ATP-dependent manner and may be involved in their biliary excretion (By similarity). {ECO:0000250|UniProtKB:O95342, ECO:0000269|PubMed:11172067, ECO:0000269|PubMed:14570929, ECO:0000269|PubMed:19228692, ECO:0000269|PubMed:22619174, ECO:0000269|PubMed:23764895}.
- 分子量
- 146.7 kDa
- UniProt
- Q9QY30
- AlphaFold
- Q9QY30
-
You are here:
