KCNQ5
(Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 5 (KCNQ5))
蛋白类型
Recombinant
产品特性
AA 1-933
宿主
小鼠
资源
HEK-293 Cells
标记
This KCNQ5 protein is labelled with His tag.
原理
Predefined custom protein recombinant Kcnq5 Protein expressed in mammalian cells.
序列
MPRHHAGGEE GGAAGLWVRS GAAAAAGAGG GRPGSGMKDV ESGRGRVLLN SAAARGDGLL LLGTRAAALG GGGGGLRESR RGKQGARMSL LGKPLSYTSS QSCRRNVKYR RVQNYLYNVL ERPRGWAFVY HAFVFLLVFG CLILSVFSTI PEHTKLASSC LLILEFVMIV VFGLEFIIRI WSAGCCCRYR GWQGRLRFAR KPFCVIDTIV LIASIAVVSA KTQGNIFATS ALRSLRFLQI LRMVRMDRRG GTWKLLGSVV YAHSKELITA WYIGFLVLIF SSFLVYLVEK DANKEFSTYA DALWWGTITL TTIGYGDKTP LTWLGRLLSA GFALLGISFF ALPAGILGSG FALKVQEQHR QKHFEKRRNP AANLIQCVWR SYAADEKSVS IATWKPHLKA LHTCSPTKKE QGEASSSQKL SFKERVRMAS PRGQSIKSRQ ASVGDRRSPS TDITAEGSPT KVQKSWSFND RTRFRPSLRL KSSQPKPVID ADTALGIDDV YDEKGCQCDV SVEDLTPPLK TVIRAIRIMK FHVAKRKFKE TLRPYDVKDV IEQYSAGHLD MLCRIKSLQT RVDQILGKGQ MTSDKKSREK ITAEHETTDD PSMLARVVKV EKQVQSIESK LDCLLDIYQQ VLRKGSASAL TLASFQIPPF ECEQTSDYQS PVDSKDLSGS AQNSGCLTRS ASANISRGLQ FILTPNEFSA QTFYALSPTM HSQATQVPMS QNDGSSVVAT NNIANQISAA PKPAAPTTLQ IPPPLSAIKH LSRPEPLLSN PTGLQESISD VTTCLVASKE SVQFAQSNLT KDRSLRKSFD MGGETLLSVR PMVPKDLGKS LSVQNLIRST EELNLQFSGS ESSGSRGSQD FYPKWRESKL FITDEEVGAE ETETDTFDGT PPPAGEAAFS SDSLRTGRSR SSQNICKTGD STDALSLPHV KLN Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
特异性
If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
产品特性
Key Benefits:
Predefined custom protein - from design to production - by highly experienced protein experts.
Protein expressed in mammalian cells and purified in one-step affinity chromatography
The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
State-of-the-art algorithm used for plasmid design (Gene synthesis).
This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
纯度
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
KCNQ5
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, SDS, WB
custom-made
KCNQ5
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, SDS, WB
应用备注
We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
限制
仅限研究用
状态
Liquid
缓冲液
The buffer composition is at the discretion of the manufacturer.
注意事项
Avoid repeated freeze-thaw cycles.
储存条件
-80 °C
储存方法
Store at -80°C.
有效期
12 months
抗原
KCNQ5
(Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 5 (KCNQ5))
Potassium voltage-gated channel subfamily KQT member 5 (KQT-like 5) (Potassium channel subunit alpha KvLQT5) (Voltage-gated potassium channel subunit Kv7.5),FUNCTION: Associates with KCNQ3 to form a potassium channel which contributes to M-type current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons. Therefore, it is important in the regulation of neuronal excitability. May contribute, with other potassium channels, to the molecular diversity of a heterogeneous population of M-channels, varying in kinetic and pharmacological properties, which underlie this physiologically important current. {ECO:0000269|PubMed:15963599}.