SMC1B Protein (AA 1-1248) (His tag)
custom-made
SMC1B
宿主: 小鼠
宿主: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- 抗原 See all SMC1B 蛋白
- SMC1B (Structural Maintenance of Chromosomes 1B (SMC1B))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-1248
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This SMC1B protein is labelled with His tag.
- 原理
- Made-to-order recombinant Smc1b Protein expressed in mammalian cells.
- 序列
- MGHLELLLVE NFKSWRGRQV IGPFKRFTCI IGPNGSGKSN VMDALSFVMG EKTTNLRVKN IQELIHGAHT GKPVSSSASV TIIYIEDSGE EKTFTRIIRG GCSEYHFGDK PVSRSVYVAQ LENIGIIVKA QNCLVFQGTV ESISMKKPKE RTQFFEEIST SGEFIGEYEA KKKKLQKAEE DAQFHFNVKK NVAAERKHAK IEKEEAEHYQ NLLEELKINK IQLMLFQLYY NEEKINVLNT ELEQMDGNLS VVKDTLSHHE NIFKAKKKDY GMLTRQLQQT AKELKSVEAI LNQKRPQYIK AKENTSHHLK KLDLSKKLIT DNEKQCSKQE DGIRALVAEL ADLDRAWKSF EKQMEEKILQ KGRDIELENS QLDRYKLLKE QVRRKVGIMT QQLEKLQWEQ KAEKERLAFE KRRHGDTQGN LKQIKEQIEE HKKRIEKLEE YTKTCMDCLE DKKQQEEALK KEIENTKSRM SEVNEELSLI RNELQNAGID NHEGKRQQKR AEVLEHLKRL YPDSVFGRLL DLCHPIHKKY QLAVTKLFGR YMVAIVVASE KIAKDCIRFL KAERAEPETF LALDYLDIKP INERLREIKG CKMMIDVIKT QFPQLKKVIQ FVCGNGLVCE TVEEARHIAF GGPERRKAVA LDGTLFLKSG VISGGSSDLK HKALCWDEKE LHNLRDKRSQ LVQELKELMK TLRKETDLKQ IQTLVQGTNT RLKYSQNELE MIKKKHLATF YREQSQLQSE LLNIDSQCTM LSEGINKQQQ KIEEFQDKID EVEDDIFQDF CEEIGVENIR EFENKHVKQQ QENDQKRLEF EKQKTRLNIQ LEYSRNQLKK KLNNIDTLKT TIQKGKEDID NLKKTEEECL KIVEELMVKQ EQIKEVLATQ SSNIEKIHIQ IEEERKKVLA VDREVGKLQK EVVIIQGSLE QKLLEKHNLL LDCKVQDIDI SLVLGSLEDI IEMELTETES TQATADIYEK EASIQIDYSP LREDLKALQS DKEVEAHLTL LLQQVASQEN TLLKTTAPNL RAQENLKTVR DKFQESADVF EASRKEARIC RQEFEQVKRR RYDAFSQCFE HISVSIDQIY KKLCRNNSAQ AFLSPENPEE PYLDGISYNC VAPGKRFMPM DNLSGGEKCV AALALLFAVH SFRPAPFFVL DEVDAALDNT NIGKVSSYIK EQSQEQFQMI IISLKEEFYS KADALIGVYP EHNECMFSHV LTLDLSKYPD TEDQEGSRSH RKPRVPRVSM SPKSPQSR Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- 特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- 产品特性
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- 质量等级
- custom-made
- Top Product
- Discover our top product SMC1B 蛋白
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Structural Maintenance of Chromosomes 1B (SMC1B) (AA 1-1235) protein (His tag)
custom-made SMC1B 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- 应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- The buffer composition is at the discretion of the manufacturer.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C.
- 有效期
- 12 months
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- 抗原
- SMC1B (Structural Maintenance of Chromosomes 1B (SMC1B))
- 别名
- Smc1b (SMC1B 产品)
- 背景
- Structural maintenance of chromosomes protein 1B (SMC protein 1B) (SMC-1-beta) (SMC-1B),FUNCTION: Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I. {ECO:0000269|PubMed:11564881, ECO:0000269|PubMed:15146193}.
- 分子量
- 144.5 kDa
- UniProt
- Q920F6
- AlphaFold
- Q920F6
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