IKZF4 Protein (AA 1-586) (His tag)
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- 抗原 See all IKZF4 蛋白
- IKZF4 (IKAROS Family Zinc Finger 4 (Eos) (IKZF4))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-586
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This IKZF4 protein is labelled with His tag.
- 原理
- Made-to-order recombinant Ikzf4 Protein expressed in mammalian cells.
- 序列
- MHTPPALPRR FQGGGRVRTP GSHRQGKDNL ERELSGGCAP DFLPQAQDSN HFIMESLFCE SSGDSSLEKE FLGAPVGPSV STPNSQHSSP SRSLSANSIK VEMYSDEESS RLLGPDERLL DKDDSVIVED SLSEPLGYCD GSGPEPHSPG GIRLPNGKLK CDVCGMVCIG PNVLMVHKRS HTGERPFHCN QCGASFTQKG NLLRHIKLHS GEKPFKCPFC NYACRRRDAL TGHLRTHSVS SPTVGKPYKC NYCGRSYKQQ STLEEHKERC HNYLQSLSTD AQALTGQPGD EIRDLEMVPD SMLHPSTERP TFIDRLANSL TKRKRSTPQK FVGEKQMRFS LSDLPYDVNA SGGYEKDVEL VAHHGLEPGF GGSLAFVGTE HLRPLRLPPT NCISELTPVI SSVYTQMQPI PSRLELPGSR EAGEGPEDLG DGGPLLYRAR GSLTDPGASP SNGCQDSTDT ESNHEDRIGG VVSLPQGPPP QPPPTIVVGR HSPAYAKEDP KPQEGLLRGT PGPSKEVLRV VGESGEPVKA FKCEHCRILF LDHVMFTIHM GCHGFRDPFE CNICGYHSQD RYEFSSHIVR GEHKVG Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- 特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- 产品特性
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- 质量等级
- custom-made
- Top Product
- Discover our top product IKZF4 蛋白
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IKAROS Family Zinc Finger 4 (Eos) (IKZF4) (AA 1-585) protein (His tag)
custom-made IKZF4 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
IKAROS Family Zinc Finger 4 (Eos) (IKZF4) (AA 1-544) protein (GST tag)IKZF4 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
IKAROS Family Zinc Finger 4 (Eos) (IKZF4) (AA 2-108) protein (GST tag)IKZF4 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
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- 应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- The buffer composition is at the discretion of the manufacturer.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C.
- 有效期
- 12 months
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- 抗原
- IKZF4 (IKAROS Family Zinc Finger 4 (Eos) (IKZF4))
- 别名
- Ikzf4 (IKZF4 产品)
- 背景
- Zinc finger protein Eos (Ikaros family zinc finger protein 4),FUNCTION: DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems. Essential for the inhibitory function of regulatory T-cells (Treg). Mediates FOXP3-mediated gene silencing in regulatory T-cells (Treg) via recruitment of corepressor CTBP1 (PubMed:19696312). {ECO:0000269|PubMed:10218586, ECO:0000269|PubMed:17403896, ECO:0000269|PubMed:19696312}.
- 分子量
- 64.2 kDa
- UniProt
- Q8C208
- AlphaFold
- Q8C208
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