SCRIB Protein (AA 1-1612) (His tag)
custom-made
SCRIB
宿主: 小鼠
宿主: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- 抗原 See all SCRIB 蛋白
- SCRIB (Scribbled Homolog (SCRIB))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-1612
- 宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This SCRIB protein is labelled with His tag.
- 原理
- Made-to-order recombinant Scrib Protein expressed in mammalian cells.
- 序列
- MLKCIPLWRC NRHVESVDKR HCSLQVVPEE IYRYSRSLEE LLLDANQLRE LPKPFFRLLN LRKLGLSDNE IQRLPPEVAN FMQLVELDVS RNDIPEIPES IKFCKALEIA DFSGNPLSRL PDGFTQLRSL AHLALNDVSL QALPGDVGNL ANLVTLELRE NLLKSLPASL SFLVKLEQLD LGGNDLEVLP DTLGALPNLR ELWLDRNQLS ALPPELGNLR RLVCLDVSEN RLEELPVELG GLALLTDLLL SQNLLQRLPE GIGQLKQLSI LKVDQNRLCE VTEAIGDCEN LSELILTENL LTALPHSLGK LTKLTNLNVD RNHLEVLPPE IGGCVALSVL SLRDNRLAVL PPELAHTAEL HVLDVAGNRL RSLPFALTHL NLKALWLAEN QAQPMLRFQT EDDAQTGEKV LTCYLLPQQP LPSLEDAGQQ SSPSESCSDA PLSRVSVIQF EDTLEGEEDA EEAAAEKRGL QRRATPHPSE LKVMKRGIEE RRNEAFVCKP DPSPPSPSEE EKRLSAESAL SGGSVPSAST ASEGEPEILP AEVQGLGQHE AMPAQEEYTE DDYNEPTVHF AEDTLIPRED GESEEGQPEA AWPLPSGRQR LIRKDTPHYK KHFKISKLPQ PEAVVALLQG VQTDREGPTA GWHNGPHTPW APRAHEEEEE EEEENRDEEE GEATTEEDDK EEAVASAPSV KGVSFDQANN LLIEPARIEE EELTLTIVRQ TGGLGISIAG GKGSTPYKGD DEGIFISRVS EEGPAARAGV RVGDKLLEVN GVALQDAEHH EAVEALRGAG AAVQMRVWRE RMVEPENAVT ITPLRPEDDY SPREWRGGGL RLPLLQPETP VSLRQRHAAC LVRSEKGLGF SIAGGKGSTP YRAGDGGIFI SRIAEGGAAH RAGTLQVGDR VLSINGVDMT EARHDHAVSL LTAASPTISL LLERETGGTY PPSPPPHSSP TPAATVAATV STAVPGEPLL PRLSPSLLAT ALEGPYPVEE ICLPRAGGPL GLSIVGGSDH SSHPFGVQDP GVFISKVLPR GLAARCGLRV GDRILAVNGQ DVREATHQEA VSALLRPCLE LCLLVRRDPP PPGMRELCIQ KAPGEKLGIS IRGGAKGHAG NPCDPTDEGI FISKVSPTGA AGRDGRLRVG LRLLEVNQQS LLGLTHAEAV QLLRSVGDTL TVLVCDGFDT STTTALEVSP GVIANPFAAG LGHRNSLESI SSIDRELSPE GPGKEKELAS QALPWESESA ETTGRNLEPL KLDYRALAAL PSAGSLQRGP SATTGGKTTE APCSPGSQQP PSPDELPANV KQAYRAFAAV PTVHPPENSA TQPPTPGPAA SPEQLSFRER QKYFELEVRV PQAEGPPKRV SLVGADDLRK MQEEEARKLQ QKRAQMLREE AVTSGPDMGL ASDRESPDDQ QEAEQPWAVP SHAGGSSPSS PPPLGGNAPV RTAKAERRHQ ERLRMQSPEL PAPERALSPA ERRALEAEKR ALWRAARMKS LEQDALRAQM VLSKSQEGRG KRGPLERLAE APSPAPTPSP TPLEDFGLQT SASPGRLSPD FVEELRTLEA SPSPGSQEED GEVALVLLGR PSPGAVGPED MTLCSSRRSV RPGRRGLGPV PS Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- 特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- 产品特性
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- 质量等级
- custom-made
- Top Product
- Discover our top product SCRIB 蛋白
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Scribbled Homolog (SCRIB) (AA 1-1630) protein (His tag)
custom-made SCRIB 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Scribbled Homolog (SCRIB) (AA 33-443) protein (His-SUMO Tag)SCRIB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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- 应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- The buffer composition is at the discretion of the manufacturer.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C.
- 有效期
- 12 months
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- 抗原
- SCRIB (Scribbled Homolog (SCRIB))
- 别名
- Scrib (SCRIB 产品)
- 背景
- Protein scribble homolog (Scribble) (Protein LAP4),FUNCTION: Scaffold protein involved in different aspects of polarized cell differentiation regulating epithelial and neuronal morphogenesis and T-cell polarization (PubMed:12499390, PubMed:18716323, PubMed:19041750, PubMed:18329370). Via its interaction with CRTAM, required for the late phase polarization of a subset of CD4+ T-cells, which in turn regulates TCR-mediated proliferation and IFNG and IL22 production (PubMed:18329370). Most probably functions in the establishment of apico-basal cell polarity (PubMed:19041750). May function in cell proliferation regulating progression from G1 to S phase and as a positive regulator of apoptosis for instance during acinar morphogenesis of the mammary epithelium (PubMed:19041750). May also function in cell migration and adhesion and hence regulate cell invasion through MAPK signaling (PubMed:18716323). May play a role in exocytosis and in the targeting of synaptic vesicles to synapses (PubMed:19458197). Functions as an activator of Rac GTPase activity. {ECO:0000269|PubMed:12499390, ECO:0000269|PubMed:18329370, ECO:0000269|PubMed:18716323, ECO:0000269|PubMed:19041750, ECO:0000269|PubMed:19458197}.
- 分子量
- 174.1 kDa
- UniProt
- Q80U72
- AlphaFold
- Q80U72
- 途径
- Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Tube Formation, Synaptic Vesicle Exocytosis, Asymmetric Protein Localization
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