PLEKHM2 Protein (AA 1-1018) (His tag)
Quick Overview for PLEKHM2 Protein (AA 1-1018) (His tag) (ABIN7564240)
抗原
See all PLEKHM2 蛋白蛋白类型
宿主
资源
纯度
质量等级
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产品特性
- AA 1-1018
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标记
- This PLEKHM2 protein is labelled with His tag.
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原理
- Predefined custom protein recombinant Plekhm2 Protein expressed in mammalian cells.
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序列
- MEPREVKDRI LENISLSVKK LQSYFAACED ETPAIRNHDK VLQRLCEHLD HALLYGLQDL SSGYWVLVVH FTRREAIRQI EVLQHVATNL GRSRAWLYLA LNENSLESYL RLFQENLGLL QKYYVRNALV CSHDHLTLFL TLVSGLEFIR FDLDLDAPYL DLAPYMPDYY KPQYLLDFED RLPSSVHGSD SLSLNSFNSV TSTNLEWDDS AIAPSSEDGD LTDTISGPRS TASDLTSSKT STKSPTQRHN PFNEEQAETA SSDTTPVHTT SQEKEEAQAP DQPDACTELE VIRVTKKKKI GKKKKTKLDE DASPLHPTSS QQKCGQQGEG DGLVGTPGLA RDPSDTVLAS PQEQGEGLSS TAGSSELSEL SQMGLLIPEM KDTSMECLGQ PLSKVIDKLH GQLDPSTWCS HADPPEQSFR AGSPGEAPEK PPFCDFSEGL PAPMDFYRFT VESPSTVAPG GGHHDPPGPS QPLHVPGSPA AALQEEEEGG RGEGQTSQPV EDRQGEEIQE PEPQEPDSQL PLVSQEPLVS QEPVPEPVSQ PEPGTHEALC KLKRDQPSPC LSSAEDSGVE EGQGSPSEMT HPSEFRVDNN HLLLLMIHVF RENEEQLFKM IRMSTGHMEG NLQLLYVLLT DCYVYLLRKG ATEKPYLVEE AVSYNELDYV SVGLDQQTVK LVCTNRRKQF LLDTADVALA ELFLASLKSA MIKGCREPPY PSILTDATME KLALAKFVAQ ESKCEASAVT VHFYGLVHWE DPMEEALGPV PCQCSPAEGT ITKEGMLHYK ASTSYLGKEH WKACFVVLSN GILYQYPDRT DVIPLLSVNM GGEQCGGCRR SNTTDRPHAF QVILADRPCL ELSADSEAEM ADWMQHLCQA VSKGVIPQGI APSPCIPCCL VITEDRLFTC HEDCQTSFFR SLGTARLADI TAISTELGKE YCVLEFSQDS PQLLQPWVIY LSCTSELDRF LTALSSGWKA IYQVDLPHKA IHEASIKQKF EDALSLIHSA WQRSDSLCRG RASRDPWC Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
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特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
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产品特性
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
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Pleckstrin Homology Domain Containing, Family M (With RUN Domain) Member 2 (PLEKHM2) (AA 1-1019) protein (His tag)
custom-made PLEKHM2 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Pleckstrin Homology Domain Containing, Family M (With RUN Domain) Member 2 (PLEKHM2) (AA 1-440) protein (GST tag)PLEKHM2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Pleckstrin Homology Domain Containing, Family M (With RUN Domain) Member 2 (PLEKHM2) protein (Myc-DYKDDDDK Tag)PLEKHM2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The buffer composition is at the discretion of the manufacturer.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -80 °C
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储存方法
- Store at -80°C.
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有效期
- 12 months
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- PLEKHM2 (Pleckstrin Homology Domain Containing, Family M (With RUN Domain) Member 2 (PLEKHM2))
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别名
- Plekhm2
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背景
- Pleckstrin homology domain-containing family M member 2 (PH domain-containing family M member 2),FUNCTION: Plays a role in lysosomes movement and localization at the cell periphery acting as an effector of ARL8B. Required for ARL8B to exert its effects on lysosome location, recruits kinesin-1 to lysosomes and hence direct their movement toward microtubule plus ends. Binding to ARL8B provides a link from lysosomal membranes to plus-end-directed motility. Critical factor involved in NK cell-mediated cytotoxicity. Drives the polarization of cytolytic granules and microtubule-organizing centers (MTOCs) toward the immune synapse between effector NK lymphocytes and target cells. Required for maintenance of the Golgi apparatus organization. May play a role in membrane tubulation. {ECO:0000250|UniProtKB:Q8IWE5}.
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分子量
- 112.7 kDa
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UniProt
- Q80TQ5
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AlphaFold
- Q80TQ5
抗原
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