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DVL2 Protein (AA 1-736) (His tag)

custom-made DVL2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7563881
发货至: 中国
  • 抗原 See all DVL2 蛋白
    DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))
    蛋白类型
    Recombinant
    产品特性
    AA 1-736
    宿主
    • 7
    • 1
    小鼠
    资源
    • 4
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This DVL2 protein is labelled with His tag.
    原理
    Made-to-order recombinant Dvl2 Protein expressed in mammalian cells.
    序列
    MAGSSAGGGG VGETKVIYHL DEEETPYLVK IPVPAERITL GDFKSVLQRP AGAKYFFKSM DQDFGVVKEE ISDDNARLPC FNGRVVSWLV SSDTPQPEVA PPAHESRTEL VPPPPPLPPL PPERTSGIGD SRPPSFHPNV SSSHENLEPE TETESVVSLR RDRPRRRDSS EHGAGGHRPG GPSRLERHLA GYESSSTLMT SELESTSLGD SDEDDTMSRF SSSTEQSSAS RLLKRHRRRR KQRPPRMERT SSFSSVTDST MSLNIITVTL NMEKYNFLGI SIVGQSNERG DGGIYIGSIM KGGAVAADGR IEPGDMLLQV NDMNFENMSN DDAVRVLRDI VHKPGPIVLT VAKCWDPSPQ AYFTLPRNEP IQPIDPAAWV SHSAALTGAF PAYPGSSSMS TITSGSSLPD GCEGRGLSVH MDMASVTKAM AAPESGLEVR DRMWLKITIP NAFLGSDVVD WLYHHVEGFP ERREARKYAS GLLKAGLIRH TVNKITFSEQ CYYVFGDLSG GCESYLVNLS LNDNDGSSGA SDQDTLAPLP GATPWPLLPT FSYQYPAPHP YSPQPPPYHE LSSYTYGGGS ASSQHSEGSR SSGSTRSDGG AGRTGRPEER APESKSGSGS ESELSSRGGS LRRGGEPGGT GDGGPPPSRG STGAPPNLRA LPGLHPYGAP SGMALPYNPM MVVMMPPPPP PVSTAVQPPG APPVRDLGSV PPELTASRQS FHMAMGNPSE FFVDVM Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
    特异性
    If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
    产品特性
    Key Benefits:
    • Made to order protein - from design to production - by highly experienced protein experts.
    • Protein expressed in mammalian cells and purified in one-step affinity chromatography
    • The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
    • State-of-the-art algorithm used for plasmid design (Gene synthesis).
    This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

    If you are not interested in a full length protein, please contact us for individual protein fragments.

    The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
    纯度
    > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
    质量等级
    custom-made
  • 应用备注
    We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    The buffer composition is at the discretion of the manufacturer.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -80 °C
    储存方法
    Store at -80°C.
    有效期
    12 months
  • 抗原
    DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))
    别名
    Dvl2 (DVL2 产品)
    背景
    Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2),FUNCTION: Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Participates both in canonical and non-canonical Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. {ECO:0000269|PubMed:17199046, ECO:0000269|PubMed:20947020, ECO:0000269|PubMed:21189423}.
    分子量
    78.9 kDa
    UniProt
    Q60838
    AlphaFold
    Q60838
    途径
    Tube Formation
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