PTGER3 Protein (AA 1-365) (His tag)
custom-made
PTGER3
宿主: 小鼠
宿主: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- 抗原 See all PTGER3 蛋白
- PTGER3 (Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-365
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This PTGER3 protein is labelled with His tag.
- 原理
- Made-to-order recombinant Ptger3 Protein expressed in mammalian cells.
- 序列
- MASMWAPEHS AEAHSNLSST TDDCGSVSVA FPITMMVTGF VGNALAMLLV SRSYRRRESK RKKSFLLCIG WLALTDLVGQ LLTSPVVILV YLSQRRWEQL DPSGRLCTFF GLTMTVFGLS SLLVASAMAV ERALAIRAPH WYASHMKTRA TPVLLGVWLS VLAFALLPVL GVGRYSVQWP GTWCFISTGP AGNETDPARE PGSVAFASAF ACLGLLALVV TFACNLATIK ALVSRCRAKA AVSQSSAQWG RITTETAIQL MGIMCVLSVC WSPLLIMMLK MIFNQMSVEQ CKTQMGKEKE CNSFLIAVRL ASLNQILDPW VYLLLRKILL RKFCQIRDHT NYASSSTSLP CPGSSALMWS DQLER Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- 特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- 产品特性
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- 质量等级
- custom-made
- Top Product
- Discover our top product PTGER3 蛋白
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Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) (AA 1-390) protein (His tag)
custom-made PTGER3 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) (AA 1-388) protein (GST tag)PTGER3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3) (AA 1-90) protein (GST tag)PTGER3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- The buffer composition is at the discretion of the manufacturer.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C.
- 有效期
- 12 months
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- 抗原
- PTGER3 (Prostaglandin E Receptor 3 (Subtype EP3) (PTGER3))
- 别名
- Ptger3 (PTGER3 产品)
- 背景
- Prostaglandin E2 receptor EP3 subtype (PGE receptor EP3 subtype) (PGE2 receptor EP3 subtype) (Prostanoid EP3 receptor),FUNCTION: Receptor for prostaglandin E2 (PGE2) (PubMed:1372606, PubMed:8381413, PubMed:8223569). Required for normal development of fever in response to pyrinogens, including IL1B, prostaglandin E2 and bacterial lipopolysaccharide (LPS) (PubMed:9751056). Required for normal potentiation of platelet aggregation by prostaglandin E2, and thus plays a role in the regulation of blood coagulation (PubMed:11535576). Required for increased HCO3(-) secretion in the duodenum in response to mucosal acidification, and thereby contributes to the protection of the mucosa against acid-induced ulceration (PubMed:10535876). Not required for normal kidney function, normal urine volume and osmolality (PubMed:9843913). {ECO:0000269|PubMed:10535876, ECO:0000269|PubMed:11535576, ECO:0000269|PubMed:1372606, ECO:0000269|PubMed:8223569, ECO:0000269|PubMed:8381413, ECO:0000269|PubMed:9751056, ECO:0000269|PubMed:9843913}., FUNCTION: [Isoform Alpha]: Receptor for prostaglandin E2 (PGE2), ligand binding activates a signaling cascade via G(i) proteins that leads to inhibition of adenylate cyclase (PubMed:1372606, PubMed:8381413). Shows high agonist-independent constitutive inhibition of adenylate cyclase (PubMed:8223569). {ECO:0000269|PubMed:1372606, ECO:0000269|PubMed:8223569, ECO:0000269|PubMed:8381413}., FUNCTION: [Isoform Beta]: Receptor for prostaglandin E2 (PGE2), ligand binding activates a signaling cascade via G(i) proteins that leads to inhibition of adenylate cyclase. Requires much higher ligand concentrations than isoform Alpha for activation (PubMed:8381413). Does not display agonist-independent constitutive inhibition of adenylate cyclase (PubMed:8223569). {ECO:0000269|PubMed:8223569, ECO:0000269|PubMed:8381413}., FUNCTION: [Isoform Gamma]: Receptor for prostaglandin E2 (PGE2), ligand binding can activate several distinct signaling cascades, resulting in activation or inhibition of adenylate cyclase. {ECO:0000269|PubMed:8223569}.
- 分子量
- 40.1 kDa
- UniProt
- P30557
- AlphaFold
- P30557
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