SPSB2 Protein (AA 1-264) (His tag)
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- 抗原 See all SPSB2 蛋白
- SPSB2 (SplA/ryanodine Receptor Domain and SOCS Box Containing 2 (SPSB2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-264
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This SPSB2 protein is labelled with His tag.
- 原理
- Made-to-order recombinant Spsb2 Protein expressed in mammalian cells.
- 序列
- MGQTALARGS SSTPTSQALY SDFSPPEGLE ELLSAPPPDL VAQRHHGWNP KDCSENIDVK EGGLCFERRP VAQSTDGVRG KRGYSRGLHA WEISWPLEQR GTHAVVGVAT ALAPLQADHY AALLGSNSES WGWDIGRGKL YHQSKGLEAP QYPAGPQGEQ LVVPERLLVV LDMEEGTLGY SIGGTYLGPA FRGLKGRTLY PSVSAVWGQC QVRIRYMGER RVEEPQSLLH LSRLCVRHAL GDTRLGQIST LPLPPAMKRY LLYK Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- 特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- 产品特性
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- 质量等级
- custom-made
- Top Product
- Discover our top product SPSB2 蛋白
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SplA/ryanodine Receptor Domain and SOCS Box Containing 2 (SPSB2) (AA 1-263) protein (His tag)
custom-made SPSB2 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
SplA/ryanodine Receptor Domain and SOCS Box Containing 2 (SPSB2) (AA 1-263) protein (His tag)SPSB2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
SplA/ryanodine Receptor Domain and SOCS Box Containing 2 (SPSB2) (AA 1-263) protein (GST tag)SPSB2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
SplA/ryanodine Receptor Domain and SOCS Box Containing 2 (SPSB2) protein (Myc-DYKDDDDK Tag)SPSB2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- The buffer composition is at the discretion of the manufacturer.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C.
- 有效期
- 12 months
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- 抗原
- SPSB2 (SplA/ryanodine Receptor Domain and SOCS Box Containing 2 (SPSB2))
- 别名
- Spsb2 (SPSB2 产品)
- 背景
- SPRY domain-containing SOCS box protein 2 (SSB-2) (Gene-rich cluster protein C9),FUNCTION: Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:20603330). Negatively regulates nitric oxide (NO) production and limits cellular toxicity in activated macrophages by mediating the ubiquitination and proteasomal degradation of NOS2 (PubMed:20603330). Acts as a bridge which links NOS2 with the ECS E3 ubiquitin ligase complex components ELOC and CUL5 (By similarity). {ECO:0000250|UniProtKB:Q99619, ECO:0000269|PubMed:20603330}.
- 分子量
- 28.9 kDa
- UniProt
- O88838
- AlphaFold
- O88838
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