RABGEF1 Protein (AA 1-491) (His tag)
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- 抗原 See all RABGEF1 蛋白
- RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-491
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This RABGEF1 protein is labelled with His tag.
- 原理
- Made-to-order recombinant Rabgef1 Protein expressed in mammalian cells.
- 序列
- MSLKSERRGI HVDQSELLCK KGCGYYGNPA WQGFCSKCWR EEYHKARQRQ IQEDWELAER LQREEEEAFA SSQSSQGAQS LTFSKFEEKK TNEKTRKVTT VKKFFSASSR AGSKKEIQEA KAPSPSINRQ TSIETDRVTK EFIDFLKTFH KTGQEVYKQT KMFLEAMPYK RDLSIEEQSE CTQDFYQNVA ERMQTRGKVP PEKVEKIMDQ IEKHIMTRLY KFVFCPETTD DEKKDLAIQK RIRALHWVTP QMLCVPVNEE IPEVSDMVVK AITDIIEMDS KRVPRDKLAC ITRCSKHIFN AIKITKNEPA SADDFLPTLI YIVLKGNPPR LQSNIQYITR FCNPSRLMTG EDGYYFTNLC CAVAFIEKLD AQSLNLSQED FDRYMSGQTS PRKQESESWP PEACLGVKQM YKNLDLLSQL NERQERIMNE AKKLEKDLID WTDGIAKEVQ DIVEKYPLEI KPPNQPLAAI DSENVENDKL PPPLQPQVYA G Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- 特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- 产品特性
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- 质量等级
- custom-made
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RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1) (AA 1-491) protein (GST tag)
RABGEF1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1) (AA 1-491), (full length) protein (His-SUMO Tag)RABGEF1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1) protein (Myc-DYKDDDDK Tag)RABGEF1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- The buffer composition is at the discretion of the manufacturer.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C.
- 有效期
- 12 months
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- 抗原
- RABGEF1 (RAB Guanine Nucleotide Exchange Factor (GEF) 1 (RABGEF1))
- 别名
- Rabgef1 (RABGEF1 产品)
- 背景
- Rab5 GDP/GTP exchange factor (Rabex-5),FUNCTION: Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A (By similarity). Can act as a ubiquitin ligase (By similarity). {ECO:0000250}.
- 分子量
- 56.9 kDa
- UniProt
- Q9JM13
- AlphaFold
- Q9JM13
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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