FUT2 Protein (AA 1-347) (His tag)
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- 抗原 See all FUT2 蛋白
- FUT2 (Fucosyltransferase 2 (Secretor Status Included) (FUT2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-347
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This FUT2 protein is labelled with His tag.
- 原理
- Made-to-order recombinant Fut2 Protein expressed in mammalian cells.
- 序列
- MASAQVPFSF PLAHFLIFVF VTSTIIHLQQ RIVKLQTLSE KELQAVQMSS PNAARTDMQQ SAKLQGIFTI NSIGRLGNQM GEYATLFALA RMNGRLAFIP ESMHNALAPI FRISLPVLHS DTARRIPWQN YHLNDWMEER YRHIPGQYVR FTGYPCSWTF YHHLRPEILK EFTLHDHVRE EAQAFLRGLR VNGSQPSTFV GVHVRRGDYV HVMPKVWKGV VADRGYLEKA LDRFRARYSS PVFVVTSNGM AWCRENINTS LGDVVFAGNG IEGSPAKDFA LLTQCNHTIM TIGTFGIWAA YLAGGDTIYL ANYTLPDSPF LKIFKPAAAF LPEWMGIPAD LSPLLKH Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- 特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- 产品特性
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- 质量等级
- custom-made
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Fucosyltransferase 2 (Secretor Status Included) (FUT2) (AA 1-343) protein (His tag)
custom-made FUT2 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Fucosyltransferase 2 (Secretor Status Included) (FUT2) (AA 51-150) protein (GST tag)FUT2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Fucosyltransferase 2 (Secretor Status Included) (FUT2) (AA 1-153) protein (GST tag)FUT2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- The buffer composition is at the discretion of the manufacturer.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C.
- 有效期
- 12 months
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- 抗原
- FUT2 (Fucosyltransferase 2 (Secretor Status Included) (FUT2))
- 别名
- Fut2 (FUT2 产品)
- 背景
- Galactoside alpha-(1,2)-fucosyltransferase 2 (Alpha(1,2)FT 2) (Fucosyltransferase 2) (GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2) (GDP-fucose: beta-galactoside alpha1,2-fucosyltransferase) (MFUT-II) (Secretory blood group protein 2) (Type 1 galactoside alpha-(1,2)-fucosyltransferase FUT2) (EC 2.4.1.69) (Type 2 galactoside alpha-(1,2)-fucosyltransferase FUT2) (EC 2.4.1.344),FUNCTION: Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose on both O- and N-linked glycans chains of cell surface glycoproteins and glycolipids and the resulting epitope regulates several processes such as cell-cell interaction including host-microbe interaction, cell surface expression and cell proliferation (PubMed:11018479, PubMed:11368156, PubMed:14967068, PubMed:11323419, PubMed:27161092, PubMed:19706747). Preferentially fucosylates gangliosides GA1 and GM1 in the antrum, cecum and colon and in the female reproductive organs (PubMed:11713270, PubMed:14967068). Fucosylated host glycoproteins or glycolipids mediate interaction with intestinal microbiota influencing its composition (PubMed:27161092, PubMed:19706747). Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble ABO blood group antigen synthesis pathway (PubMed:11323419). {ECO:0000269|PubMed:11018479, ECO:0000269|PubMed:11323419, ECO:0000269|PubMed:11368156, ECO:0000269|PubMed:11713270, ECO:0000269|PubMed:14967068, ECO:0000269|PubMed:19706747, ECO:0000269|PubMed:27161092}.
- 分子量
- 39.2 kDa
- UniProt
- Q9JL27
- AlphaFold
- Q9JL27
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