RRP1B Protein (AA 1-724) (His tag)
custom-made
RRP1B
宿主: 小鼠
宿主: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- 抗原 See all RRP1B products
- RRP1B (Ribosomal RNA Processing 1 Homolog B (RRP1B))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-724
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This RRP1B protein is labelled with His tag.
- 原理
- Made-to-order recombinant Rrp1b Protein expressed in mammalian cells.
- 序列
- MALAMQSSEF QFAQRLASSE KGVRDRAVRK LRQYLSARTQ SDTGSFSQEE LLKIWKGLFY CMWVQDEPLL QEELANIISQ LIHVVNSLEA QYLFIQTFWQ TMNREWQGID KLQLDKYYML IRLVLRQSFE VLKRNAWEES QITLFLDILM KEILSPESQS PNGVRTHLID VYLEELTTVG GAELLADQNL KLIDPFCRIA AKTKDHTLVQ TVARGVFEVI VDQSACVPQE SVEERKTKED GSGFPTKALA CRKAVSGKKA ALDECLRDGV IGSRERDICA ALKDSGSPLQ FDYKAVADRL LEIANSKSTP PFNRKRLCRL VRKFQDLCEG NGAPLSSAED NGQRRHKRKR KKLLESEKGD TVSPAAEEDS GGHIHKKKRK KRKRSHFQPD TQNLDAVAVP KVPDSESEPD TAQRQAPCGQ ACVTEPTAEA VSSIGENSSK PTPVMPIHNK RKRPRKKKLR AHKEICKSTT LPQEDMSKND AVSGHSQSSA AHISSSEGVQ AQKRKRKLGA LPDSSSDLPV QKSGTPTSPV EGKDGQTTLP RCKRSQKKTA SSTLDPCDPS SQKPAISKKK KKTMKLMSNG VLESNPGQIQ ALGSNRTLKK PLKTEDDFVK FDTRFLPKPL FFRKAKNSSA TRPQGPAGQL NKTPSSSKKV TFGLNRNMTA EFKKTDKSIL VSPTGLSRVA FNPEQRPLHG VLKTATSSPA STPLSPMRLP ATTPKRRPRA ADFF Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- 特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- 产品特性
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- 质量等级
- custom-made
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Ribosomal RNA Processing 1 Homolog B (RRP1B) (AA 1-758) protein (His tag)
custom-made RRP1B 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- 应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- The buffer composition is at the discretion of the manufacturer.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C.
- 有效期
- 12 months
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- 抗原
- RRP1B (Ribosomal RNA Processing 1 Homolog B (RRP1B))
- 别名
- Rrp1b (RRP1B 产品)
- 背景
- Ribosomal RNA processing protein 1 homolog B (RRP1-like protein B),FUNCTION: Positively regulates DNA damage-induced apoptosis by acting as a transcriptional coactivator of proapoptotic target genes of the transcriptional activator E2F1 (By similarity). Likely to play a role in ribosome biogenesis by targeting serine/threonine protein phosphatase PP1 to the nucleolus (By similarity). Involved in regulation of mRNA splicing (PubMed:23604122). Inhibits SIPA1 GTPase activity (PubMed:18081427). Involved in regulating expression of extracellular matrix genes (PubMed:18081427). Associates with chromatin and may play a role in modulating chromatin structure (By similarity). {ECO:0000250|UniProtKB:Q14684, ECO:0000269|PubMed:18081427, ECO:0000269|PubMed:23604122}.
- 分子量
- 80.6 kDa
- UniProt
- Q91YK2
- AlphaFold
- Q91YK2
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