Predefined custom protein recombinant Klf11 Protein expressed in mammalian cells.
序列
MHSPGSTGPG DGRAADIMDI CESILERKRH DSERSTCSVL EQTDIEAVEA LVCMSSWGQR SQMRPLTPVS DSGDVTTAVL MDTAAPDLPK DFHSFSTLCI TPPQSPELTE PSTGTPVPSQ VVNSKGCMVT ALPPSPAGGP RTLSKREPLE PASGSSCRAV MTSVIRHTGE SPAPTRFPTG PTQEQRASDS GEGQERLLDH LEALQDTRLA NGLLVTNLVS CQPCLHKSGG SFPTDKGQQT GWPAAVQTCL PKNPESDLSR KITPLISVPV SSPPVLCQMI PVAGQNGLFS AFLKPPTQLP AGTIKPILPQ AASMSQPVFM GPPVPQGTVM LVLPQNTFPQ PAACPSSVMA IGNTKLLPLA PAPVFLASSQ NCAPQVDFSR RRNYVCNFPG CRKTYFKSSH LKAHLRTHTG EKPFTCSWDG CDKKFARSDE LSRHRRTHTG EKKFVCPVCD RRFMRSDHLT KHARRHMTTK KIPGWQAEVG KLNRITLAES PGSILEPLPA SG Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
特异性
If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
产品特性
Key Benefits:
Predefined custom protein - from design to production - by highly experienced protein experts.
Protein expressed in mammalian cells and purified in one-step affinity chromatography
The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
State-of-the-art algorithm used for plasmid design (Gene synthesis).
This protein is a predefined protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
纯度
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
KLF11
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
KLF11
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
应用备注
We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
限制
仅限研究用
状态
Liquid
缓冲液
The buffer composition is at the discretion of the manufacturer.
Krueppel-like factor 11 (TGFB-inducible early growth response protein 2b) (Transforming growth factor-beta-inducible early growth response protein 3) (TGFB-inducible early growth response protein 3) (TIEG-3),FUNCTION: Transcription factor. Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding sites inhibiting cell growth (By similarity). Represses transcription of SMAD7 which enhances TGF-beta signaling. Induces apoptosis. {ECO:0000250|UniProtKB:O14901, ECO:0000269|PubMed:14697507, ECO:0000269|PubMed:18189266}.