GRAMD4 Protein (AA 1-633) (His tag)
custom-made
GRAMD4
宿主: 小鼠
宿主: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- 抗原 See all GRAMD4 products
- GRAMD4 (GRAM Domain Containing 4 (GRAMD4))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-633
- 宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This GRAMD4 protein is labelled with His tag.
- 原理
- Predefined custom protein recombinant Gramd4 Protein expressed in mammalian cells.
- 序列
- MGIASHSAFR ERESSPTGAS LDASPRPWDK GLSGREPPRH VQVRPRSAVL NMLRRLDRIR FRGHKREDLL DLAESPNASD TECGDEIPLK TPRPSPRDSE ELRDPAGPGT LIMAAGVQDF NRTEFDRLNE IKGHLEIALL EKHFLQEELR KLREETNSEM LRQELDRERQ RRIELEQKMQ EVLKARSEEQ PAQPQQPPKG QSQASNGTGT ERRSQGLASR VQKWFYERFG EYIEDFRFQP EENTVETEEP LSARRLTENM RRLKRGAKPV TNFVKNLSAL SDWYSIYTSA IAFTVYMNAV WHGWAIPMFL FLAILRLSLN YLIARGWRIQ WSIVPEVSEA VEPAKEDLTV SEKFQLVLDV AQKAQNLFGK MADILEKIKN LFMWVQPETT QKLYVALWAA FLASCFFPYR LVGLAVGLYA GIKFFLIDFI FKRCPRLRAK YDTPYIIWRS LPTDPQLKER AGATVSRRLQ TASSRSYVSS APAGLSKDED AGRFHSTKKG NFHEIFNLTE NERPLAVCEN GWRCCLINRD RKMPTDYIRN GVLYVTENYL CFESSKSGSS KRNKVIKLMD ITDIQKYKVL SVLPGSGMGI AVSTPSTQKP LVFGAMVHRD EAFETIFSQY VKITSAAASG GDS Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
- 特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- 产品特性
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- 质量等级
- custom-made
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GRAM Domain Containing 4 (GRAMD4) (AA 1-578) protein (His tag)
custom-made GRAMD4 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- 应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- The buffer composition is at the discretion of the manufacturer.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C.
- 有效期
- 12 months
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- 抗原
- GRAMD4 (GRAM Domain Containing 4 (GRAMD4))
- 别名
- Gramd4 (GRAMD4 产品)
- 背景
- GRAM domain-containing protein 4 (Death-inducing protein),FUNCTION: Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53 (By similarity). Inhibits TLR9 response to nucelic acids and regulates TLR9-mediated innate immune response (PubMed:25917084). {ECO:0000250|UniProtKB:Q6IC98, ECO:0000269|PubMed:25917084}.
- 分子量
- 72.3 kDa
- UniProt
- Q8CB44
- AlphaFold
- Q8CB44
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