Usp17la (USP17LA)
(Ubiquitin Specific Peptidase 17-Like A (USP17LA))
蛋白类型
Recombinant
产品特性
AA 1-526
宿主
小鼠
资源
HEK-293 Cells
标记
This Usp17la protein is labelled with His tag.
原理
Made-to-order recombinant Usp17la Protein expressed in mammalian cells.
序列
MVVALSFPEA DPALSSPDAP ELHQDEAQVV EELTVNGKHS LSWESPQGPG CGLQNTGNSC YLNAALQCLT HTPPLADYML SQEHSQTCCS PEGCKLCAME ALVTQSLLHS HSGDVMKPSH ILTSAFHKHQ QEDAHEFLMF TLETMHESCL QVHRQSKPTS EDSSPIHDIF GGWWRSQIKC LLCQGTSDTY DRFLDIPLDI SSAQSVKQAL WDTEKSEELC GDNAYYCGKC RQKMPASKTL HVHIAPKVLM VVLNRFSAFT GNKLDRKVSY PEFLDLKPYL SEPTGGPLPY ALYAVLVHDG ATSHSGHYFC CVKAGHGKWY KMDDTKVTRC DVTSVLNENA YVLFYVQQAN LKQVSIDMPE GRINEVLDPE YQLKKSRRKK HKKKSPFTED LGEPCENRDK RAIKETSLGK GKVLQEVNHK KAGQKHGNTK LMPQKQNHQK AGQNLRNTEV ELDLPADAIV IHQPRSTANW GRDSPDKENQ PLHNADRLLT SQGPVNTWQL CRQEGRRRSK KGQNKNKQGQ RLLLVC Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
特异性
If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
产品特性
Key Benefits:
Made to order protein - from design to production - by highly experienced protein experts.
Protein expressed in mammalian cells and purified in one-step affinity chromatography
The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
State-of-the-art algorithm used for plasmid design (Gene synthesis).
This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
纯度
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
USP17LA
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
> 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, SDS, WB
应用备注
We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
限制
仅限研究用
状态
Liquid
缓冲液
The buffer composition is at the discretion of the manufacturer.
注意事项
Avoid repeated freeze-thaw cycles.
储存条件
-80 °C
储存方法
Store at -80°C.
有效期
12 months
抗原
Usp17la (USP17LA)
(Ubiquitin Specific Peptidase 17-Like A (USP17LA))
Ubiquitin carboxyl-terminal hydrolase 17-like protein A (USP17-A) (EC 3.4.19.12) (Deubiquitinating enzyme 1) (Ubiquitin carboxyl-terminal hydrolase DUB-1) (Ubiquitin thioesterase DUB-1) (Ubiquitin-specific-processing protease DUB-1),FUNCTION: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Has deubiquitinating enzyme activity for DNAH5, suggesting a role in the regulation of DNAH5 degradation by the ubiquitin-proteasome pathway. Has growth-suppressing activity, induces arrest in G1 phase upon controlled expression. {ECO:0000269|PubMed:18980247, ECO:0000269|PubMed:8622927}.