CENPW Protein (AA 1-86) (Fc Tag)
custom-made
CENPW
宿主: 小鼠
宿主: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- 抗原 See all CENPW 蛋白
- CENPW (Centromere Protein W (CENPW))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-86
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This CENPW protein is labelled with Fc Tag.
- 原理
- Predefined custom protein recombinant Cenpw Protein expressed in mammalian cells.
- 序列
- MAPSTTVTRR VKRKAPRAFL KRTLKQKKPH LGLGRCCDLL IHLNCLLFIQ RLAEESRTNA CESKSRVIKK DHVLAAGKVI LKKSRG Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- 特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- 产品特性
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- 质量等级
- custom-made
- Top Product
- Discover our top product CENPW 蛋白
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Centromere Protein W (CENPW) (AA 1-88) protein (His tag)
custom-made CENPW 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Centromere Protein W (CENPW) (AA 1-88) protein (GST tag)CENPW 宿主: 人 宿主: 小麦胚 Recombinant ELISA, AA, AP, WB
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- 应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- The buffer composition is at the discretion of the manufacturer.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C.
- 有效期
- 12 months
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- 抗原
- CENPW (Centromere Protein W (CENPW))
- 别名
- Cenpw (CENPW 产品)
- 背景
- Centromere protein W (CENP-W) (Cancer-up-regulated gene 2 protein),FUNCTION: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation (By similarity). The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres (By similarity). Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. CENPW has a fundamental role in kinetochore assembly and function. It is one of the inner kinetochore proteins, with most further proteins binding downstream. Required for normal chromosome organization and normal progress through mitosis (By similarity). {ECO:0000250, ECO:0000269|PubMed:17610844}.
- 分子量
- 9.7 kDa
- UniProt
- Q3URR0
- AlphaFold
- Q3URR0
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