Oct-2 Protein (AA 1-463) (His tag)
custom-made
POU2F2
宿主: 小鼠
宿主: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- 抗原 See all Oct-2 (POU2F2) 蛋白
- Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-463
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This Oct-2 protein is labelled with His tag.
- 原理
- Made-to-order recombinant Pou2f2 Protein expressed in mammalian cells.
- 序列
- MVHSSMGAPE IRMSKPLEAE KQSLDSPSEH TDTERNGPDI NHQNPQNKAS PFSVSPTGPS TKIKAEDPSG DSAPAAPPPP QPAQPHLPQA QLMLTGSQLA GDIQQLLQLQ QLVLVPGHHL QPPAQFLLPQ AQQSQPGLLP TPNLFQLPQQ TQGALLTSQP RAGLPTQPPK CLEPPSHPEE PSDLEELEQF ARTFKQRRIK LGFTQGDVGL AMGKLYGNDF SQTTISRFEA LNLSFKNMCK LKPLLEKWLN DAETMSVDSS LPSPNQLSSP SLGFDGLPGR RRKKRTSIET NVRFALEKSF LANQKPTSEE ILLIAEQLHM EKEVIRVWFC NRRQKEKRIN PCSAAPMLPS PGKPTSYSPH LVTPQGGAGT LPLSQASSSL STTVTTLSSA VGTLHPSRTA GGGGGGGGAA PPLNSIPSVT PPPPATTNST NPSPQGSHSA IGLSGLNPSA GPGLWWNPAP YQP Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- 特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- 产品特性
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- 质量等级
- custom-made
- Top Product
- Discover our top product POU2F2 蛋白
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POU domain, class 2, transcription factor 2 (POU2F2) (AA 1-479) protein (His tag)
custom-made POU2F2 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
POU domain, class 2, transcription factor 2 (POU2F2) (AA 1-400) protein (GST tag)POU2F2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- The buffer composition is at the discretion of the manufacturer.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C.
- 有效期
- 12 months
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- 抗原
- Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))
- 别名
- Pou2f2 (POU2F2 产品)
- 背景
- POU domain, class 2, transcription factor 2 (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2) (Octamer-binding protein 2) (Oct-2) (Octamer-binding transcription factor 2) (OTF-2),FUNCTION: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3') (PubMed:2011512, PubMed:1281152). Regulates IL6 expression in B cells with POU2AF1 (PubMed:23045607). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. {ECO:0000250|UniProtKB:P09086, ECO:0000269|PubMed:1281152, ECO:0000269|PubMed:17285328, ECO:0000269|PubMed:2011512, ECO:0000269|PubMed:23045607, ECO:0000269|PubMed:7935477}., FUNCTION: [Isoform OCT2.1]: Activates octamer-containing promoters. {ECO:0000269|PubMed:1281152, ECO:0000269|PubMed:2011512}., FUNCTION: [Isoform OCT2.2]: Activates octamer-containing promoters. {ECO:0000269|PubMed:1281152, ECO:0000269|PubMed:2011512}., FUNCTION: [Isoform OCT2.3]: Activates octamer-containing promoters. {ECO:0000269|PubMed:1281152, ECO:0000269|PubMed:2011512}., FUNCTION: [Isoform OCT2.4]: Represses some promoters and activate others. {ECO:0000269|PubMed:1281152, ECO:0000269|PubMed:2011512}., FUNCTION: [Isoform OCT2.5]: Represses some promoters and activate others (PubMed:1281152, PubMed:2011512). Activates the U2 small nuclear RNA (snRNA) promoter (By similarity). {ECO:0000250|UniProtKB:P09086, ECO:0000269|PubMed:1281152, ECO:0000269|PubMed:2011512}., FUNCTION: [Isoform OCT2.7]: Unable to bind to the octamer motif, but can still activate the beta-casein gene promoter at low levels. {ECO:0000269|PubMed:17285328}.
- 分子量
- 49.4 kDa
- UniProt
- Q00196
- AlphaFold
- Q00196
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