Made-to-order recombinant USP6NL Protein expressed in mammalian cells.
序列
MNSDQDVALK LAQERAEIVA KYDRGREGAE IEPWEDADYL VYKVTDRFGF LHEEELPDHN VAVERQKHLE IERTTKWLKM LKGWEKYKNT EKFHRRIYKG IPLQLRGEVW ALLLEIPKMK EETRDLYSKL KHRARGCSPD IRQIDLDVNR TFRDHIMFRD RYGVKQQSLF HVLAAYSIYN TEVGYCQGMS QITALLLMYM NEEDAFWALV KLFSGPKHAM HGFFVQGFPK LLRFQEHHEK ILNKFLSKLK QHLDSQEIYT SFYTMKWFFQ CFLDRTPFTL NLRIWDIYIF EGERVLTAMS YTILKLHKKH LMKLSMEELV EFFQETLAKD FFFEDDFVIE QLQISMTELK RAKLDLPEPG KEDEYPKKPL GQLPPELQSW GVHHLSNGQR SVGRPSPLAS GRRESGAPHR RHEHSPHPQS RTGTPERAQP PRRKSVEEES KKLKDEADFQ RKLPSGPQDS SRQYNHAAAN QNSNATSNIR KEFVPKWNKP SDVSATERTA KYTMEGKGRA AHPALAVTVP GPAEVRVSNV RPKMKALDAE DGKRGSTASQ YDNVPGPELD SGASVEEALE RAYSQSPRHA LYPPSPRKHA EPSSSPSKVS NKFTFKVQPP SHARYPSQLD GEARGLAHPP SYSNPPVYHG NSPKHFPTAN SSFASPQFSP GTQLNPSRRP HGSTLSVSAS PEKSYSRPSP LVLPSSRIEV LPVDTGAGGY SGNSGSPKNG KLIIPPVDYL PDNRTWSEVS YTYRPETQGQ SWTRDASRGN LPKYSAFQLA PFQDHGLPAV SVDSPVRYKA SPAAEDASPS GYPYSGPPPP AYHYRNRDGL SIQESVLL Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
特异性
If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
产品特性
Key Benefits:
Made to order protein - from design to production - by highly experienced protein experts.
Protein expressed in mammalian cells and purified in one-step affinity chromatography
The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
State-of-the-art algorithm used for plasmid design (Gene synthesis).
This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
纯度
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
USP6NL
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
> 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
应用备注
We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
限制
仅限研究用
状态
Liquid
缓冲液
The buffer composition is at the discretion of the manufacturer.
USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN-tre),FUNCTION: Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex. {ECO:0000269|PubMed:11099046, ECO:0000269|PubMed:17562788, ECO:0000269|PubMed:17684057}.