Cortactin Protein (CTTN) (AA 1-550) (His tag)
Our Local Distributor
北京 101111
Quick Overview for Cortactin Protein (CTTN) (AA 1-550) (His tag) (ABIN7555565)
抗原
See all Cortactin (CTTN) 蛋白蛋白类型
宿主
资源
纯度
质量等级
-
-
产品特性
- AA 1-550
-
标记
- This Cortactin protein is labelled with His tag.
-
原理
- Predefined custom protein recombinant CTTN Protein expressed in mammalian cells.
-
序列
- MWKASAGHAV SIAQDDAGAD DWETDPDFVN DVSEKEQRWG AKTVQGSGHQ EHINIHKLRE NVFQEHQTLK EKELETGPKA SHGYGGKFGV EQDRMDKSAV GHEYQSKLSK HCSQVDSVRG FGGKFGVQMD RVDQSAVGFE YQGKTEKHAS QKDYSSGFGG KYGVQADRVD KSAVGFDYQG KTEKHESQRD YSKGFGGKYG IDKDKVDKSA VGFEYQGKTE KHESQKDYVK GFGGKFGVQT DRQDKCALGW DHQEKLQLHE SQKDYKTGFG GKFGVQSERQ DSAAVGFDYK EKLAKHESQQ DYSKGFGGKY GVQKDRMDKN ASTFEDVTQV SSAYQKTVPV EAVTSKTSNI RANFENLAKE KEQEDRRKAE AERAQRMAKE RQEQEEARRK LEEQARAKTQ TPPVSPAPQP TEERLPSSPV YEDAASFKAE LSYRGPVSGT EPEPVYSMEA ADYREASSQQ GLAYATEAVY ESAEAPGHYP AEDSTYDEYE NDLGITAVAL YDYQAAGDDE ISFDPDDIIT NIEMIDDGWW RGVCKGRYGL FPANYVELRQ Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
-
特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
-
产品特性
-
Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
-
-
想要此Protein的其他选项吗？
!探索我们的目录蛋白和定制蛋白服务选项！Product表达系统ConjugateOriginPrice表达系统 Wheat germConjugate GST tagOrigin HumanPrice 5,782.24 ¥表达系统 Wheat germConjugate GST tagOrigin HumanPrice 5,782.24 ¥表达系统 HEK-293 CellsConjugate Myc-DYKDDDDK TagOrigin HumanPrice 10,600.77 ¥表达系统 Escherichia coli (E. coli)Conjugate His-IF2DI TagOrigin HumanPrice 4,668.87 ¥表达系统 Escherichia coli (E. coli)Conjugate His tagOrigin HumanPrice 5,126.92 ¥表达系统 Insect cells (Sf9)Conjugate DYKDDDDK TagOrigin HumanPrice 6,871.41 ¥表达系统 BacteriaConjugate His tagOrigin HumanPrice 3,968.25 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
-
Cortactin (CTTN) (AA 1-546) protein (His tag)
custom-made CTTN 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Cortactin (CTTN) (AA 1-513) protein (GST tag)CTTN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cortactin (CTTN) (AA 341-450) protein (GST tag)CTTN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Cortactin (CTTN) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CTTN 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
-
应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- The buffer composition is at the discretion of the manufacturer.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -80 °C
-
储存方法
- Store at -80°C.
-
有效期
- 12 months
-
-
- Cortactin (CTTN)
-
别名
- CTTN
-
背景
- Src substrate cortactin (Amplaxin) (Oncogene EMS1),FUNCTION: Contributes to the organization of the actin cytoskeleton and cell shape (PubMed:21296879). Plays a role in the formation of lamellipodia and in cell migration. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Through its interaction with CTTNBP2, involved in the regulation of neuronal spine density (By similarity). Plays a role in focal adhesion assembly and turnover (By similarity). In complex with ABL1 and MYLK regulates cortical actin-based cytoskeletal rearrangement critical to sphingosine 1-phosphate (S1P)-mediated endothelial cell (EC) barrier enhancement (PubMed:20861316). Plays a role in intracellular protein transport and endocytosis, and in modulating the levels of potassium channels present at the cell membrane (PubMed:17959782). Plays a role in receptor-mediated endocytosis via clathrin-coated pits (By similarity). Required for stabilization of KCNH1 channels at the cell membrane (PubMed:23144454). Plays a role in the invasiveness of cancer cells, and the formation of metastases (PubMed:16636290). {ECO:0000250|UniProtKB:Q60598, ECO:0000250|UniProtKB:Q66HL2, ECO:0000269|PubMed:16636290, ECO:0000269|PubMed:17959782, ECO:0000269|PubMed:21296879, ECO:0000269|PubMed:23144454}.
-
分子量
- 61.6 kDa
-
UniProt
- Q14247
-
AlphaFold
- Q14247
-
途径
- MAPK Pathway
抗原
-
