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PHC3 Protein (AA 1-983) (His tag)

custom-made PHC3 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
产品编号 ABIN7554985
发货至: 中国
  • 抗原 See all PHC3 蛋白
    PHC3 (Polyhomeotic Homolog 3 (PHC3))
    蛋白类型
    Recombinant
    产品特性
    AA 1-983
    宿主
    • 2
    • 2
    资源
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This PHC3 protein is labelled with His tag.
    原理
    Made-to-order recombinant PHC3 Protein expressed in mammalian cells.
    序列
    MDTEPNPGTS SVSTTTSSTT TTTITTSSSR MQQPQISVYS GSDRHAVQVI QQALHRPPSS AAQYLQQMYA AQQQHLMLHT AALQQQHLSS SQLQSLAAVQ ASLSSGRPST SPTGSVTQQS SMSQTSINLS TSPTPAQLIS RSQASSSTSG SITQQTMLLG STSPTLTASQ AQMYLRAQML IFTPATTVAA VQSDIPVVSS SSSSSCQSAA TQVQNLTLRS QKLGVLSSSQ NGPPKSTSQT QSLTICHNKT TVTSSKISQR DPSPESNKKG ESPSLESRST AVTRTSSIHQ LIAPASYSPI QPHSLIKHQQ IPLHSPPSKV SHHQLILQQQ QQQIQPITLQ NSTQDPPPSQ HCIPLQNHGL PPAPSNAQSQ HCSPIQSHPS PLTVSPNQSQ SAQQSVVVSP PPPHSPSQSP TIIIHPQALI QPHPLVSSAL QPGPNLQQST ANQVQATAQL NLPSHLPLPA SPVVHIGPVQ QSALVSPGQQ IVSPSHQQYS SLQSSPIPIA SPPQMSTSPP AQIPPLPLQS MQSLQVQPEI LSQGQVLVQN ALVSEEELPA AEALVQLPFQ TLPPPQTVAV NLQVQPPAPV DPPVVYQVED VCEEEMPEES DECVRMDRTP PPPTLSPAAI TVGRGEDLTS EHPLLEQVEL PAVASVSASV IKSPSDPSHV SVPPPPLLLP AATTRSNSTS MHSSIPSIEN KPPQAIVKPQ ILTHVIEGFV IQEGLEPFPV SRSSLLIEQP VKKRPLLDNQ VINSVCVQPE LQNNTKHADN SSDTEMEDMI AEETLEEMDS ELLKCEFCGK MGYANEFLRS KRFCTMSCAK RYNVSCSKKF ALSRWNRKPD NQSLGHRGRR PSGPDGAARE HILRQLPITY PSAEEDLASH EDSVPSAMTT RLRRQSERER ERELRDVRIR KMPENSDLLP VAQTEPSIWT VDDVWAFIHS LPGCQDIADE FRAQEIDGQA LLLLKEDHLM SAMNIKLGPA LKICARINSL KES Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
    特异性
    If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
    产品特性
    Key Benefits:
    • Made to order protein - from design to production - by highly experienced protein experts.
    • Protein expressed in mammalian cells and purified in one-step affinity chromatography
    • The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
    • State-of-the-art algorithm used for plasmid design (Gene synthesis).
    This protein is a made-to-order protein and will be made for the first time for your order. Our experts in the lab try to ensure that you receive soluble protein.

    If you are not interested in a full length protein, please contact us for individual protein fragments.

    The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
    纯度
    > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
    质量等级
    custom-made
  • 应用备注
    We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    The buffer composition is at the discretion of the manufacturer.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -80 °C
    储存方法
    Store at -80°C.
    有效期
    12 months
  • 抗原
    PHC3 (Polyhomeotic Homolog 3 (PHC3))
    别名
    PHC3 (PHC3 产品)
    背景
    Polyhomeotic-like protein 3 (Early development regulatory protein 3) (Homolog of polyhomeotic 3) (hPH3),FUNCTION: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. {ECO:0000269|PubMed:12167701}.
    分子量
    106.2 kDa
    UniProt
    Q8NDX5
    AlphaFold
    Q8NDX5
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