PEG10 Protein (AA 1-708) (His tag)
Quick Overview for PEG10 Protein (AA 1-708) (His tag) (ABIN7554920)
抗原
See all PEG10 蛋白蛋白类型
宿主
资源
纯度
质量等级
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产品特性
- AA 1-708
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标记
- This PEG10 protein is labelled with His tag.
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原理
- Predefined custom protein recombinant PEG10 Protein expressed in mammalian cells.
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序列
- MTERRRDELS EEINNLREKV MKQSEENNNL QSQVQKLTEE NTTLREQVEP TPEDEDDDIE LRGAAAAAAP PPPIEEECPE DLPEKFDGNP DMLAPFMAQC QIFMEKSTRD FSVDRVRVCF VTSMMTGRAA RWASAKLERS HYLMHNYPAF MMEMKHVFED PQRREVAKRK IRRLRQGMGS VIDYSNAFQM IAQDLDWNEP ALIDQYHEGL SDHIQEELSH LEVAKSLSAL IGQCIHIERR LARAAAARKP RSPPRALVLP HIASHHQVDP TEPVGGARMR LTQEEKERRR KLNLCLYCGT GGHYADNCPA KASKSSPAGK LPGPAVEGPS ATGPEIIRSP QDDASSPHLQ VMLQIHLPGR HTLFVRAMID SGASGNFIDH EYVAQNGIPL RIKDWPILVE AIDGRPIASG PVVHETHDLI VDLGDHREVL SFDVTQSPFF PVVLGVRWLS THDPNITWST RSIVFDSEYC RYHCRMYSPI PPSLPPPAPQ PPLYYPVDGY RVYQPVRYYY VQNVYTPVDE HVYPDHRLVD PHIEMIPGAH SIPSGHVYSL SEPEMAALRD FVARNVKDGL ITPTIAPNGA QVLQVKRGWK LQVSYDCRAP NNFTIQNQYP RLSIPNLEDQ AHLATYTEFV PQIPGYQTYP TYAAYPTYPV GFAWYPVGRD GQGRSLYVPV MITWNPHWYR QPPVPQYPPP QPPPPPPPPP PPPSYSTL Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
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特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
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产品特性
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified.
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Paternally Expressed 10 (PEG10) (AA 1-958) protein (His tag)
custom-made PEG10 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Paternally Expressed 10 (PEG10) (AA 1-325) protein (GST tag)PEG10 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Paternally Expressed 10 (PEG10) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)PEG10 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- The buffer composition is at the discretion of the manufacturer.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -80 °C
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储存方法
- Store at -80°C.
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有效期
- 12 months
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- PEG10 (Paternally Expressed 10 (PEG10))
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别名
- PEG10
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背景
- Retrotransposon-derived protein PEG10 (Embryonal carcinoma differentiation-regulated protein) (Mammalian retrotransposon-derived protein 2) (Myelin expression factor 3-like protein 1) (MEF3-like protein 1) (Paternally expressed gene 10 protein) (Retrotransposon gag domain-containing protein 3) (Retrotransposon-derived gag-like polyprotein) (Ty3/Gypsy-like protein),FUNCTION: Retrotransposon-derived protein that binds its own mRNA and self-assembles into virion-like capsids (PubMed:34413232). Forms virion-like extracellular vesicles that encapsulate their own mRNA and are released from cells, enabling intercellular transfer of PEG10 mRNA (PubMed:34413232). Binds its own mRNA in the 5'-UTR region, in the region near the boundary between the nucleocapsid (NC) and protease (PRO) coding sequences and in the beginning of the 3'-UTR region (PubMed:34413232). Involved in placenta formation: required for trophoblast stem cells differentiation (By similarity). Involved at the immediate early stage of adipocyte differentiation (By similarity). Overexpressed in many cancers and enhances tumor progression: promotes cell proliferation by driving cell cycle progression from G0/G1 (PubMed:12810624, PubMed:16423995, PubMed:26235627, PubMed:28193232). Enhances cancer progression by inhibiting the TGF-beta signaling, possibly via interaction with the TGF-beta receptor ACVRL1 (PubMed:15611116, PubMed:26235627, PubMed:30094509). May bind to the 5'-GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein (MBP) promoter, additional evidences are however required to confirm this result (By similarity). {ECO:0000250|UniProtKB:Q7TN75, ECO:0000269|PubMed:12810624, ECO:0000269|PubMed:15611116, ECO:0000269|PubMed:16423995, ECO:0000269|PubMed:26235627, ECO:0000269|PubMed:28193232, ECO:0000269|PubMed:30094509, ECO:0000269|PubMed:34413232}.
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分子量
- 80.2 kDa
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UniProt
- Q86TG7
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AlphaFold
- Q86TG7
抗原
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