PHF13 Protein (AA 1-300) (His tag)
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- 抗原 See all PHF13 蛋白
- PHF13 (PHD Finger Protein 13 (PHF13))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-300
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PHF13 protein is labelled with His tag.
- 原理
- Made-to-order recombinant PHF13 Protein expressed in mammalian cells.
- 序列
- MDSDSCAAAF HPEEYSPSCK RRRTVEDFNK FCTFVLAYAG YIPYPKEELP LRSSPSPANS TAGTIDSDGW DAGFSDIASS VPLPVSDRCF SHLQPTLLQR AKPSNFLLDR KKTDKLKKKK KRKRRDSDAP GKEGYRGGLL KLEAADPYVE TPTSPTLQDI PQAPSDPCSG WDSDTPSSGS CATVSPDQVK EIKTEGKRTI VRQGKQVVFR DEDSTGNDED IMVDSDDDSW DLVTCFCMKP FAGRPMIECN ECHTWIHLSC AKIRKSNVPE VFVCQKCRDS KFDIRRSNRS RTGSRKLFLD Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- 特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- 产品特性
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- 质量等级
- custom-made
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PHD Finger Protein 13 (PHF13) (AA 1-296) protein (His tag)
custom-made PHF13 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
PHD Finger Protein 13 (PHF13) (AA 1-300) protein (His tag)PHF13 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
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- 应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- The buffer composition is at the discretion of the manufacturer.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C.
- 有效期
- 12 months
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- 抗原
- PHF13 (PHD Finger Protein 13 (PHF13))
- 别名
- PHF13 (PHF13 产品)
- 背景
- PHD finger protein 13 (Survival time-associated PHD finger protein in ovarian cancer 1) (SPOC1),FUNCTION: Modulates chromatin structure and DNA damage response by regulating key determinants of chromatin compaction and DNA damage response (PubMed:19638409). Binds H3K4me3-containing chromatin and promotes DNA condensation by recruiting corepressors such as TRIM28 and H3K9 methyltransferase SETDB1 (PubMed:23034801). Required for normal chromosome condensation during the early stages of mitosis. Required for normal chromosome separation during mitosis (PubMed:19638409). Increases both chromatin-associated levels and activity of H3K9 methyltransferases, such as SETDB1, thus enhancing H3K9 trimethylation (PubMed:23034801). Essential for testicular stem-cell differentiation and sustained spermatogenesis (By similarity). {ECO:0000250|UniProtKB:Q8K2W6, ECO:0000269|PubMed:19638409, ECO:0000269|PubMed:23034801}.
- 分子量
- 33.6 kDa
- UniProt
- Q86YI8
- AlphaFold
- Q86YI8
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