SIAH3 Protein (AA 1-269) (His tag)
custom-made
SIAH3
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
-
- 抗原 See all SIAH3 products
- SIAH3 (Siah E3 Ubiquitin Protein Ligase Family Member 3 (SIAH3))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-269
- 宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This SIAH3 protein is labelled with His tag.
- 原理
- Predefined custom protein recombinant SIAH3 Protein expressed in mammalian cells.
- 序列
- MLFFTQCFGA VLDLIHLRFQ HYKAKRVFSA AGQLVCVVNP THNLKYVSSR RAVTQSAPEQ GSFHPHHLSH HHCHHRHHHH LRHHAHPHHL HHQEAGLHAN PVTPCLCMCP LFSCQWEGRL EVVVPHLRQI HRVDILQGAE IVFLATDMHL PAPADWIIMH SCLGHHFLLV LRKQERHEGH PQFFATMMLI GTPTQADCFT YRLELNRNHR RLKWEATPRS VLECVDSVIT DGDCLVLNTS LAQLFSDNGS LAIGIAITAT EVLPSEAEM Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
- 特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- 产品特性
-
Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- 质量等级
- custom-made
-
Want other Options for this Protein
!Discover Our Catalog and Custom Protein Service Options!Your project requires further customization? Contact us and discover our custom protein solutions
-
-
- 应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- The buffer composition is at the discretion of the manufacturer.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C.
- 有效期
- 12 months
-
- 抗原
- SIAH3 (Siah E3 Ubiquitin Protein Ligase Family Member 3 (SIAH3))
- 别名
- SIAH3 (SIAH3 产品)
- 背景
- Seven in absentia homolog 3 (Siah-3),FUNCTION: Negative regulator of PRKN translocation to damaged mitochondria. Acts probably by destabilizing PINK1 protein, hence inhibiting PRKN targeting to dysfunctional depolarized mitochondria. {ECO:0000269|PubMed:24270810}.
- 分子量
- 30.7 kDa
- UniProt
- Q8IW03
- AlphaFold
- Q8IW03
-
You are here:
