ZFAND5 Protein (AA 1-213) (His tag)
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- 抗原 See all ZFAND5 蛋白
- ZFAND5 (Zinc Finger, AN1-Type Domain 5 (ZFAND5))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-213
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This ZFAND5 protein is labelled with His tag.
- 原理
- Made-to-order recombinant ZFAND5 Protein expressed in mammalian cells.
- 序列
- MAQETNQTPG PMLCSTGCGF YGNPRTNGMC SVCYKEHLQR QQNSGRMSPM GTASGSNSPT SDSASVQRAD TSLNNCEGAA GSTSEKSRNV PVAALPVTQQ MTEMSISRED KITTPKTEVS EPVVTQPSPS VSQPSTSQSE EKAPELPKPK KNRCFMCRKK VGLTGFDCRC GNLFCGLHRY SDKHNCPYDY KAEAAAKIRK ENPVVVAEKI QRI Sequence without tag. The proposed Purification-Tag is based on experiences with the expression system, a different complexity of the protein could make another tag necessary. In case you have a special request, please contact us.
- 特异性
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- 产品特性
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Key Benefits:
- Made to order protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our made-to-order proteins in comparison to ordering custom made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - 纯度
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- 质量等级
- custom-made
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Zinc Finger, AN1-Type Domain 5 (ZFAND5) (AA 1-213) protein (His tag)
ZFAND5 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Zinc Finger, AN1-Type Domain 5 (ZFAND5) (AA 1-213) protein (GST tag)ZFAND5 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Zinc Finger, AN1-Type Domain 5 (ZFAND5) (Transcript Variant C) protein (Myc-DYKDDDDK Tag)ZFAND5 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Zinc Finger, AN1-Type Domain 5 (ZFAND5) (Transcript Variant A) protein (Myc-DYKDDDDK Tag)ZFAND5 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Zinc Finger, AN1-Type Domain 5 (ZFAND5) (Transcript Variant B) protein (Myc-DYKDDDDK Tag)ZFAND5 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Zinc Finger, AN1-Type Domain 5 (ZFAND5) protein (DYKDDDDK Tag)ZFAND5 宿主: 人 宿主: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- The buffer composition is at the discretion of the manufacturer.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C.
- 有效期
- 12 months
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- 抗原
- ZFAND5 (Zinc Finger, AN1-Type Domain 5 (ZFAND5))
- 别名
- ZFAND5 (ZFAND5 产品)
- 背景
- AN1-type zinc finger protein 5 (Zinc finger A20 domain-containing protein 2) (Zinc finger protein 216),FUNCTION: Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation. {ECO:0000269|PubMed:14754897}.
- 分子量
- 23.1 kDa
- UniProt
- O76080
- AlphaFold
- O76080
- 途径
- Platelet-derived growth Factor Receptor Signaling
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