IL-4 蛋白
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- 抗原 See all IL-4 (IL4) 蛋白
- IL-4 (IL4) (Interleukin 4 (IL4))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 小鼠
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资源
- 大肠杆菌(E. Coli)
- 原理
- IL-4
- 序列
- MHIHGCDKNH LREIIGILNE VTGEGTPCTE MDVPNVLTAT KNTTESELVC RASKVLRIFY LKHGKTPCLK KNSSVLMELQ RLFRAFRCLD SSISCTMNES KSTSLKDFLE SLKSIMQMDY S
- 特异性
- Chromosomal location:11 B1.3, 11 29.0 cM
- 交叉反应
- 人, Leech, 小鼠, Pig, 大鼠, Trout
- 产品特性
- Length (aa):120
- 纯度
- > 98 % by SDS-PAGE and Coomassie stain
- 内毒素水平
- < 0.1 ng/μg of protein (<1EU/μg)
- Top Product
- Discover our top product IL4 蛋白
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- 应用备注
- The ED50 was determined by the dose-dependent proliferation of murine HT-2 cells is < 2.0 ng/mL, corresponding to a specific activity of > 5 x 10^5 units/mg.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
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- 抗原
- IL-4 (IL4) (Interleukin 4 (IL4))
- 别名
- IL-4 (IL4 产品)
- 背景
- Il4, Il-4, BSF-1,Interleukin 4 (IL-4) is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. It was initially identified as a B cell differentiation factor (BCDF), as well as a B cell stimulatory factor (BSF1). IL-4 has since been shown to have multiple biological effects on hematopoietic and non-hematopoietic cells, including B and T cells, monocytes, macrophages, mast cells, myeloid and erythroid progenitors, fibroblasts, and endothelial cells. Rat, mouse and human IL-4 are species-specific in their activities.
- 分子量
- 13.5 kDa
- 基因ID
- 16189
- NCBI登录号
- NM_021283, NP_067258
- UniProt
- P07750
- 途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
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