IL-4 蛋白
Quick Overview for IL-4 蛋白 (ABIN7539338)
抗原
See all IL-4 (IL4) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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                                            原理
- IL-4
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                                            序列
- MHIHGCDKNH LREIIGILNE VTGEGTPCTE MDVPNVLTAT KNTTESELVC RASKVLRIFY LKHGKTPCLK KNSSVLMELQ RLFRAFRCLD SSISCTMNES KSTSLKDFLE SLKSIMQMDY S
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                                            特异性
- Chromosomal location:11 B1.3, 11 29.0 cM
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                                            交叉反应
- 人, Leech, 小鼠, Pig, 大鼠, Trout
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                                            产品特性
- Length (aa):120
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                                            内毒素水平
- < 0.1 ng/μg of protein (<1EU/μg)
 
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                                            应用备注
- The ED50 was determined by the dose-dependent proliferation of murine HT-2 cells is < 2.0 ng/mL, corresponding to a specific activity of > 5 x 10^5 units/mg.
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                                            限制
- 仅限研究用
 
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                                            状态
- Lyophilized
 
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    - IL-4 (IL4) (Interleukin 4 (IL4))
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                                            别名
- IL-4
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                                            背景
- Il4, Il-4, BSF-1,Interleukin 4 (IL-4) is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. It was initially identified as a B cell differentiation factor (BCDF), as well as a B cell stimulatory factor (BSF1). IL-4 has since been shown to have multiple biological effects on hematopoietic and non-hematopoietic cells, including B and T cells, monocytes, macrophages, mast cells, myeloid and erythroid progenitors, fibroblasts, and endothelial cells. Rat, mouse and human IL-4 are species-specific in their activities.
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                                            分子量
- 13.5 kDa
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                                            基因ID
- 16189
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                                            NCBI登录号
- NM_021283, NP_067258
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                                            UniProt
- P07750
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                                            途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
 抗原
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