LHCGR 蛋白
Quick Overview for LHCGR 蛋白 (ABIN7538363)
抗原
See all LHCGR 蛋白蛋白类型
宿主
资源
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原理
- Human LSHR full length protein-synthetic nanodisc
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产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) (AA 27-363) protein (His tag)
LHCGR 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) (AA 27-363) protein (His tag)LHCGR 宿主: 人 宿主: 酵母菌 Recombinant > 90 % SDS
Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) (AA 27-362) protein (His-SUMO Tag)LHCGR 宿主: 大鼠 宿主: 酵母菌 Recombinant ≥ 90 % SDS
Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) (AA 27-362) protein (His-SUMO Tag)LHCGR 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))
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别名
- LSHR
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背景
- This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia. [provided by RefSeq, Jul 2008]
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分子量
- The human full length LSHR protein has a MW of 78.6kDa
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UniProt
- P22888
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途径
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
抗原
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