Quick Overview for ILDR2 蛋白 (ABIN7538328)
抗原
蛋白类型
宿主
资源
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原理
- Human ILDR2 full length protein-synthetic nanodisc
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产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) (AA 21-184) protein (Fc Tag)
ILDR2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 92 % as determined by HPLC
Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) protein (His tag)ILDR2 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) (AA 1-186), (Extracellular) protein (GST tag)ILDR2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) (AA 21-186) protein (Fc Tag)ILDR2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2) (AA 1-186), (Extracellular) protein (His tag)ILDR2 宿主: 人 宿主: 酵母菌 Recombinant > 90 % SDS
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说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- ILDR2 (Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2))
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别名
- ILDR2
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背景
- May be involved in ER stress pathways with effects on lipid homeostasis and insulin secretion. With ILDR1 and LSR, involved in the maintain of the epithelial barrier function through the recruitment of MARVELD2/tricellulin to tricellular tight junctions. Also functions as a B7-like protein family member expressed on immune cells and inflamed tissue and with T-cell inhibitory activity.
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分子量
- The human full length ILDR2 protein has a MW of 71.2 kDa
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UniProt
- Q71H61
抗原
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