FZD8 蛋白
Quick Overview for FZD8 蛋白 (ABIN7538249)
抗原
See all FZD8 蛋白蛋白类型
宿主
资源
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原理
- Human FZD8 full length protein-synthetic nanodisc
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产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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Frizzled Family Receptor 8 (FZD8) protein (His tag)
FZD8 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
Frizzled Family Receptor 8 (FZD8) (AA 72-161) protein (GST tag)FZD8 宿主: 人 宿主: 小麦胚 Recombinant ELISA, AA, AP, WB
Frizzled Family Receptor 8 (FZD8) protein (Biotin,His-Avi Tag)FZD8 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
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说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- FZD8 (Frizzled Family Receptor 8 (FZD8))
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别名
- FZD8
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背景
- This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined. [provided by RefSeq, Jul 2008]
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分子量
- The human full length FZD8 protein has a MW of 73.3kDa
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UniProt
- Q9H461
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途径
- WNT signaling
抗原
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