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Syndecan 1 Protein (SDC1) (rFc Tag)

This Recombinant Syndecan 1 protein is expressed in HEK-293 Cells.
产品编号 ABIN7535767
发货至: 中国

Quick Overview for Syndecan 1 Protein (SDC1) (rFc Tag) (ABIN7535767)

抗原

See all Syndecan 1 (SDC1) 蛋白
Syndecan 1 (SDC1)

蛋白类型

Recombinant

宿主

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资源

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HEK-293 Cells

纯度

> 95 % by SDS-PAGE.
  • 标记

    This Syndecan 1 protein is labelled with rFc Tag.

    原理

    Recombinant Human Syndecan-1/SDC1/CD138 Protein

    序列

    QIVATNLPPE DQDGSGDDSD NFSGSGAGAL QDITLSQQTP STWKDTQLLT AIPTSPEPTG LEATAASTST LPAGEGPKEG EAVVLPEVEP GLTAREQEAT PRPRETTQLP TTHLASTTTA TTAQEPATSH PHRDMQPGHH ETSTPAGPSQ ADLHTPHTED GGPSATERAA EDGASSQLPA AEGSGEQDFT FETSGENTAV VAVEPDRRNQ SPVDQGATGA SQGLLDRKE

    特异性

    Gln23-Glu251

    过滤

    0.22 μm filtered

    内毒素水平

    <0.1EU/μg
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

    缓冲液

    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • 抗原

    Syndecan 1 (SDC1)

    别名

    Syndecan-1/SDC1/CD138

    背景

    Description: Syndecan-1 also known as SDC1 and CD138, is the most extensively studied member of the syndecan family. It is found mainly in epithelial cells, but its expression is developmentally regulated during embryonic development. Syndecan-1/SDC1/CD138 has been shown to mediate cell adhesion to several ECM molecules, and to act as a coreceptor for fibroblast growth factors, potent angiogenic growth factors involved also in differentiation. Syndecan-1/SDC1/CD138 expression is reduced during malignant transformation of various epithelia, and this loss correlates with the histological differentiation grade of squamous cell carcinomas, lacking from poorly differentiated tumours. In squamous cell carcinomas of the head and neck, positive syndecan-1 expression correlates with a more favourable prognosis. Experimental studies on the role of Syndecan-1 in malignant transformation have shown that Syndecan-1/SDC1/CD138 expression is associated with the maintenance of epithelial morphology, anchorage-dependent growth and inhibition of invasiveness in vitro.

    Name: CD138, SDC, SYND1, syndecan,SDC1,SDC,SYND1,syndecan

    基因ID

    6382

    UniProt

    P18827

    途径

    Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism
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